Neuropathic pain

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Neuropathic pain may be due to lesions or diseases affecting the somatosensory system. (Wikipedia.org)






Conferences related to Neuropathic pain

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2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

The conference program will consist of plenary lectures, symposia, workshops andinvitedsessions of the latest significant findings and developments in all the major fields ofbiomedical engineering.Submitted papers will be peer reviewed. Accepted high quality paperswill be presented in oral and postersessions, will appear in the Conference Proceedings and willbe indexed in PubMed/MEDLINE & IEEE Xplore


2019 44th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)

Science, technology and applications spanning the millimeter-waves, terahertz and infrared spectral regions


2019 International Conference on Virtual Rehabilitation (ICVR)

The goal of the conference series is to provide an overview of applied and clinical research on technologies in the field of virtual rehabilitation.


2018 17th IEEE International Conference on Machine Learning and Applications (ICMLA)

The conference focuses on all areas of machine learning and its applications in medicine, biology, industry, manufacturing, security, education, virtual environments, game playing big data, deep learning, and problem solving.


2018 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

We solicit high-quality original research papers (including significant work-in-progress) in any aspect of bioinformatics and biomedicine. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged

  • 2017 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    We solicit high-quality original research papers (including significant work-in-progress) in any aspect of bioinformatics and biomedicine. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged Relevant topics

  • 2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    We solicit high-quality original research papers (including significant work-in-progress) on any aspect of bioinformatics, biomedicine and healthcare informatics. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged

  • 2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    We solicit high-quality original research papers (including significant work-in-progress) on any aspect of bioinformatics, biomedicine and healthcare informatics. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged

  • 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    high-quality original research papers (including significant work-in-progress)in any aspect of bioinformatics and biomedicine. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition;knowledge representation; databases; data modeling; combinatorics; stochastic modeling;string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and heir application in life science domain are especially encouraged

  • 2013 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    original research papers (including significant work-in-progress)in any aspect of bioinformatics and biomedicine. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition;knowledge representation; databases; data modeling; combinatorics; stochastic modeling;string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and heir application in life science domain are especially encouraged

  • 2012 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    BIBM 2012 solicits high-quality original research papers (including significant work-in-progress) in any aspect of bioinformatics, biomedicine and healthcare informatics. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged.

  • 2011 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    We solicit high-quality original research papers (including significant work-in-progress) in any aspect of bioinformatics and biomedicine.

  • 2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    IEEE BIBM 2010 will provide a general forum for disseminating the latest research in bioinformatics and biomedicine. It is a multidisciplinary conference that brings together academic and industrial scientists from computer science, biology, chemistry, medicine, mathematics and statistics.

  • 2009 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    IEEE BIBM 2009 will provide a general forum for disseminating the latest research in bioinformatics and biomedicine. It is a multidisciplinary conference that brings together academic and industrial scientists from computer science, biology, chemistry, medicine, mathematics and statistics.

  • 2008 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)

    IEEE BIBM 2008 will provide a general forum for disseminating the latest research in bioinformatics and biomedicine. It is a multidisciplinary conference that brings together academic and industrial scientists from computer science, biology, chemistry, medicine, mathematics and statistics. It will exchange research results and address open issues in all aspects of bioinformatics and biomedicine and provide a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, si

  • 2007 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)


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Periodicals related to Neuropathic pain

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Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


Magnetics, IEEE Transactions on

Science and technology related to the basic physics and engineering of magnetism, magnetic materials, applied magnetics, magnetic devices, and magnetic data storage. The Transactions publishes scholarly articles of archival value as well as tutorial expositions and critical reviews of classical subjects and topics of current interest.


Microwave Magazine, IEEE

Focuses on applications of technical knowledge. IEEE Microwave Magazine concentrates on general-interest, applications-oriented articles as well as technical articles in the field of microwave theory and techniques including components, devices, circuits, and systems involving the generation, modulation, demodulation, control, transmission and detection of microwaves.


Neural Systems and Rehabilitation Engineering, IEEE Transactions on

Rehabilitation aspects of biomedical engineering, including functional electrical stimulation, acoustic dynamics, human performance measurement and analysis, nerve stimulation, electromyography, motor control and stimulation, and hardware and software applications for rehabilitation engineering and assistive devices.


Plasma Science, IEEE Transactions on

Plasma science and engineering, including: magnetofluid dynamics and thermionics; plasma dynamics; gaseous electronics and arc technology; controlled thermonuclear fusion; electron, ion, and plasma sources; space plasmas; high-current relativistic electron beams; laser-plasma interactions; diagnostics; plasma chemistry and colloidal and solid-state plasmas.


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Most published Xplore authors for Neuropathic pain

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Xplore Articles related to Neuropathic pain

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The role of infrared thermal imaging (ITI) in management of neuropathic pain

Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. N, 1999

The value of infrared thermal imaging (ITI) is shown to be limited to evaluation of neurovascular dysfunction. It provides useful diagnostic and therapeutic information in the management of neuropathic pain.


Spinal cord stimulation for complex regional pain syndrome

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009

The therapy of spinal cord stimulation (SCS) is based on producing an electrical field on the dorsal surface of the spinal cord that blocks only neuropathic pain (ie, pain from damage to the nervous system). Most SCS devices deliver a biphasic pulse consisting of a pair of equal amplitude pulses with opposite polarity. SCS therapy is based on the gate ...


Molecular Mechanism of Neuropathic Pain

International Conference on Informatics Education and Research for Knowledge-Circulating Society (icks 2008), 2008

There are many patients suffering from neuropathic pain. Reactive oxygen species (ROS) is thought to be a mediator of neuropathic pain. In addition, neuropatic pain is aggravated by low temperature. However, receptor of ROS and low temperature is unknown. TRPA1 is activated by pain- producing agents such as allyl isothiocyanate or formaldehyde. We hypothesized that TRPA1 is receptor of ROS ...


Treatment for neuropathic pain and chronic inflammation using LASER in animal models

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015

The ST36 (Zusanli) acupuncture point is used to treat inflammatory processes, pain and gastrointestinal disturbs. For this reason, the aim of the present study was to evaluate the antinociceptive effect of Low-level Laser Treatment (LLLT) on ST36 acupoint using models of chronic nociception and inflammation. Male Swiss mice were treated with LLLT on ST36 30 minutes before the mechanical allodynia ...


Decoding Neuropathic Pain in the Central Nervous System Through the Peri-Stimulus Histogram Method

2013 39th Annual Northeast Bioengineering Conference, 2013

Neuropathic pain develops as a result of damage to the peripheral or central nervous system from lesions or other forms of dysfunction. In a clinical setting, neuropathic pain is difficult to treat because the underlying mechanisms and pathophysiology are not well known. In order to investigate the connection between neuropathic pain and motor cortex encoding, rats with spared nerve injuries ...


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Educational Resources on Neuropathic pain

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IEEE-USA E-Books

  • The role of infrared thermal imaging (ITI) in management of neuropathic pain

    The value of infrared thermal imaging (ITI) is shown to be limited to evaluation of neurovascular dysfunction. It provides useful diagnostic and therapeutic information in the management of neuropathic pain.

  • Spinal cord stimulation for complex regional pain syndrome

    The therapy of spinal cord stimulation (SCS) is based on producing an electrical field on the dorsal surface of the spinal cord that blocks only neuropathic pain (ie, pain from damage to the nervous system). Most SCS devices deliver a biphasic pulse consisting of a pair of equal amplitude pulses with opposite polarity. SCS therapy is based on the gate control theory of pain and has been used for the treatment of diverse conditions of neuropathic pain, including complex regional pain syndromes (CRPS). In addition to CRPS, SCS is helpful in patients with failed back surgery syndrome, degenerative disk disease, and in patients with peripheral neuropathies. When used in the right patient, SCS provides significant pain relief in a majority of patients with CRPS. This review focuses on the effects of SCS on CRPS. In addition, an overview of the state of the art technologies used for implantable SCS medical devices is also provided.

  • Molecular Mechanism of Neuropathic Pain

    There are many patients suffering from neuropathic pain. Reactive oxygen species (ROS) is thought to be a mediator of neuropathic pain. In addition, neuropatic pain is aggravated by low temperature. However, receptor of ROS and low temperature is unknown. TRPA1 is activated by pain- producing agents such as allyl isothiocyanate or formaldehyde. We hypothesized that TRPA1 is receptor of ROS and low temperature on nociceptor. The purpose of present study is to investigate the validity of this hypothesis using Ca<sup>2+</sup> imagining, patch clamp. Deep cooling (&lt;17degC) and ROS activates TRPA1 expressing HEK293 cells. These results indicate that TRPA1 is receptor of ROS and low temperature.

  • Treatment for neuropathic pain and chronic inflammation using LASER in animal models

    The ST36 (Zusanli) acupuncture point is used to treat inflammatory processes, pain and gastrointestinal disturbs. For this reason, the aim of the present study was to evaluate the antinociceptive effect of Low-level Laser Treatment (LLLT) on ST36 acupoint using models of chronic nociception and inflammation. Male Swiss mice were treated with LLLT on ST36 30 minutes before the mechanical allodynia (von Frey) performed on the partial sciatic nerve ligation (PSNL) method and Complete Freund's Adjuvant (CFA). The results demonstrated that application of LLLT on ST36 inhibited the mechanical allodynia response induced by PSNL and CFA, with total reversion at 30 minutes after application. Long-term treatment of animals with LLLT on the same acupoint, once a day, also reduced the PNSL and CFA-induced mechanical allodynia response during 8 days of treatment. As conclusion, the results demonstrated that photonic stimulus on ST36 with LLLT produces antinociceptive effect in chronic models of nociception and inflammation. These findings suggest that LLLT may constitute an important therapeutic alternative to control chronic pain.

  • Decoding Neuropathic Pain in the Central Nervous System Through the Peri-Stimulus Histogram Method

    Neuropathic pain develops as a result of damage to the peripheral or central nervous system from lesions or other forms of dysfunction. In a clinical setting, neuropathic pain is difficult to treat because the underlying mechanisms and pathophysiology are not well known. In order to investigate the connection between neuropathic pain and motor cortex encoding, rats with spared nerve injuries (SNI) were utilized as models. Using active stimulation methods, somatosensory data from both lesioned and sham paws was collected via two microarray electrodes in the hindlimb sensory motor cortices. The peri- stimulus time histogram (PSTH) method was employed for data classification. Compared to the sham group, the SNI group exhibited significant mean neuron response increases in the somatosensory cortex contralateral to the lesion site when exposed to a noxious surface. In addition, the uninjured limb also showed increased mean neuron responses in ipsilateral and contralateral sensorimotor cortices. These results support the idea that neuropathic pain is encoded in the central nervous system and not restricted to the periphery. Further exploration of these central nervous system mechanisms is required in order to develop a neurocomputational model of neuropathic pain.

  • Infrared thermographic imaging for the assessment of temperature asymmetries in reflex sympathetic dystrophy

    In this on going study, we investigating the usefulness of thermographic patterns as a tool for evaluating reflex sympathetic dystrophy based on results from a clinical trial. Asymmetric thermal patterns and sympathetic responses on the pain side and contra lateral pain-free side after applying cold stimulations are observed. The thermal pattern on the painful side before entry into the drug or placebo treatment is warmer or cooler by at least 1/spl deg/C and spread over a large area. On the other hand, no remarkable difference is observed between the two sides in LDI blood velocity images. After entry into the drug, thermography shows temperatures on the painful site increase or decrease than the pain-free contra lateral side. In this article we present some cases in which thermography is used to track physiological conditions associated with chronic neuropathic pain.

  • An MRI-compatible and quantifiable mechanical stimulator for allodynia in a rat model of neuropathic pain

    We developed an MRI-compatible and quantifiable mechanical stimulator for rats. Functional MRI (fMRI) was used to investigate brain activations resulting from mechanical stimulation in normal rats and in a rat model of neuropathic pain. In the previous MRI-compatible mechanical stimulator, stimulation intensity was not adjustable. In this study, the strength of mechanical stimulation was controlled by von Frey filaments, which were used for mechanical nociception assessment. It provides us to investigate correlations between behavioral sensitivities in von Frey tests and BOLD signal changes during mechanical stimulation. In order to transmit mechanical force to a stimulation site under the strong magnetic field of a 7-T MRI system, a tube-rod structure consisting of nonmagnetic materials was used. The mechanical stimulation evoked a change in blood oxygenation level dependent (BOLD) signals in normal rats. Changes in brain activation were investigated at around- and supra-threshold conditions of mechanical nociception using the filaments for 15 g and 60 g forces. The mechanical stimulation from the 60-g-force filament, which was over the mechanical nociceptive threshold, induced strong brain activation in the areas related to nociceptive pain perception. This result was consistent with that associated with strong electrical stimulation. Mechanical stimulation in the neuropathic pain model evoked brain activity even at around-threshold conditions of mechanical nociception. Higher brain activity in the neuropathic pain model compared with normal rats was considered to be associated with allodynia.

  • Effects of low amplitude pulsed radiofrequency stimulation with different waveform in rats for neuropathic pain

    Pulsed-radiofrequency (PRF) electrical stimulation has been widely used for chronic pain treatment. It has been demonstrated with advantages of low temperature over traditional continuous radiofrequency (CRF) lesions with higher amplitude and mono polar electrode to treat pain in clinics (frequency 500 KHz, Pulse duration 20 msec, Amplitude 45 V, Treatment 2 min). We compare the effects of different pulse waveforms and PRF parameters (Pulse duration 25 ms, Treatment duration 5 min, low amplitude of 2.5/1.25 V) with a miniature bi-polar electrode on Dorsal root ganglion (DRG). The pain relief effect due to PRF is evaluated by using Von Frey method for the pain threshold index based on behavior response to mechanical stimulus of various strengths. Experimental results of Von Frey Score show that the sinusoidal group has higher responses than the square wave one. Both fast and secondary expressed proteins of c-fos and pp38 are measured from spinal cord tissue sectioning slides to characterize the pain associated inflammatory responses and their responses due to PRF stimulation.

  • The role of infrared thermography in diagnosis and management of pain

    Infrared thermal imaging (ITG) is a sensitive test. It's use is limited to diagnosis of the thermal function of the sympathetic system. It objectively identified areas of sympathetic nerve damage (usually hyperthermic) or partial sympathetic nerve dysfunction (usually hypothermic). As is the case with all other diagnostic tests, it does not diagnose a disease, but it helps identify the nature of nerve dysfunction responsible for pain. In neuropathic pain syndromes-such as RSD-thermographic testing is more sensitive than scintigraphic bone scan. Thermography requires impeccable technique to exclude artifactual false positive results. Thermography is instrumental in accurate evaluation of the nerve dysfunction and in avoidance of unnecessary surgery and other invasive procedures. It is instrumental in separating pain with simple emotional connotation vs neuropathic pain causing disturbance of the limbic system and emotional disturbance. This test helps the clinician to manage the pain more properly.

  • Gestural Interaction and Visual Illusion for Lower Limbs’ Neuropathic Pain Treatment

    Pain caused by a lesion or a disease affecting the somatosensory nervous system is known as Neuropathic pain. It has been shown that neuropathic pain can be treated with the combination of simultaneous transcranial direct current stimulation and the generation of the visual illusion that the patient retains control of the affected limbs. For persons with neuropathic pain in the lower limbs, the visual illusion consists of an image of the patient walking normally. Such a visual illusion has classically been generated by using a physical mirror and a projector. The objective of this paper is to develop and validate a computer-based version of the visual illusion, including Gestural Control. The developed system has been validated in a trial and has been successfully implanted in daily clinical practice in a reference neurorehabilitation hospital. A retrospective statistical analysis shows that the patients treated with the computer-based system reduce their pain level significantly more than the patients treated with the mirror and projector treatment before the introduction of the computer-based version. Furthermore, it also makes possible to bring the therapy to the home of the patients, where the treatment can be self-administered while still being monitored by the clinical staff.



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