Conferences related to Nerve tissues

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2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

The conference program will consist of plenary lectures, symposia, workshops and invitedsessions of the latest significant findings and developments in all the major fields of biomedical engineering.Submitted papers will be peer reviewed. Accepted high quality papers will be presented in oral and postersessions, will appear in the Conference Proceedings and will be indexed in PubMed/MEDLINE


2020 IEEE International Conference on Image Processing (ICIP)

The International Conference on Image Processing (ICIP), sponsored by the IEEE SignalProcessing Society, is the premier forum for the presentation of technological advances andresearch results in the fields of theoretical, experimental, and applied image and videoprocessing. ICIP 2020, the 27th in the series that has been held annually since 1994, bringstogether leading engineers and scientists in image and video processing from around the world.


2020 IEEE International Conference on Plasma Science (ICOPS)

IEEE International Conference on Plasma Science (ICOPS) is an annual conference coordinated by the Plasma Science and Application Committee (PSAC) of the IEEE Nuclear & Plasma Sciences Society.


2020 IEEE International Solid- State Circuits Conference - (ISSCC)

ISSCC is the foremost global forum for solid-state circuits and systems-on-a-chip. The Conference offers 5 days of technical papers and educational events related to integrated circuits, including analog, digital, data converters, memory, RF, communications, imagers, medical and MEMS ICs.


2020 IEEE International Symposium on Circuits and Systems (ISCAS)

The International Symposium on Circuits and Systems (ISCAS) is the flagship conference of the IEEE Circuits and Systems (CAS) Society and the world’s premier networking and exchange forum for researchers in the highly active fields of theory, design and implementation of circuits and systems. ISCAS2020 focuses on the deployment of CASS knowledge towards Society Grand Challenges and highlights the strong foundation in methodology and the integration of multidisciplinary approaches which are the distinctive features of CAS contributions. The worldwide CAS community is exploiting such CASS knowledge to change the way in which devices and circuits are understood, optimized, and leveraged in a variety of systems and applications.


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Periodicals related to Nerve tissues

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Applied Superconductivity, IEEE Transactions on

Contains articles on the applications and other relevant technology. Electronic applications include analog and digital circuits employing thin films and active devices such as Josephson junctions. Power applications include magnet design as well asmotors, generators, and power transmission


Biomedical Circuits and Systems, IEEE Transactions on

The Transactions on Biomedical Circuits and Systems addresses areas at the crossroads of Circuits and Systems and Life Sciences. The main emphasis is on microelectronic issues in a wide range of applications found in life sciences, physical sciences and engineering. The primary goal of the journal is to bridge the unique scientific and technical activities of the Circuits and Systems ...


Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


Circuits and Systems Magazine, IEEE


Computational Biology and Bioinformatics, IEEE/ACM Transactions on

Specific topics of interest include, but are not limited to, sequence analysis, comparison and alignment methods; motif, gene and signal recognition; molecular evolution; phylogenetics and phylogenomics; determination or prediction of the structure of RNA and Protein in two and three dimensions; DNA twisting and folding; gene expression and gene regulatory networks; deduction of metabolic pathways; micro-array design and analysis; proteomics; ...


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Xplore Articles related to Nerve tissues

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Micromachined Electrode Arrays with Form-Fitting Profile for Auditory Nerve Prostheses

2005 IEEE Engineering in Medicine and Biology 27th Annual Conference, 2006

This paper reports the design, fabrication and simulation of a novel micromachined electrode array with a form-fitting profile for use in auditory nerve prostheses. A 10times10 electrode array is created in a 1mm<sup>2</sup> area using bulk micromachining technology. The space between the individual electrodes within the array is filled with a layer of SU-8 molded to conform to the curved ...


The Measurement of Body Currents

Transactions of the American Institute of Electrical Engineers, 1941

D.C. potentials are associated with static cellular life and are a product of metabolism. A.C. potentials are associated with many tissues controlling or responding to movement. Brain tissue is the most highly developed and exists normally in a state of constant, irregular electrical activity.


6A-4 Focused Ultrasound Potential to Initiate Spreading Depression for Disruption of Blood Brain Barrier

2007 IEEE Ultrasonics Symposium Proceedings, 2007

Blood-brain barrier (BBB) has long been known to impede the delivery of therapeutic and diagnostic agents into the central nervous system. Although ultrasound with microbubbles has been shown to disrupt the BBB, we presently examine another ultrasound-induced mechanism for opening of the BBB: ultrasound induction of spreading depression. In this process, local physical changes induced by the ultrasound pressure field, ...


FE Assessment of an Interspinous Implant (ISS)

2006 International Conference on Biomedical and Pharmaceutical Engineering, 2006

The main objective of this work is the demonstration of a conceptual approach for efficient interspinous implant evaluation and design using finite element (FE) method. A novel dynamic stabilization system (Interspinous spacer (ISS), registered in France under FR05/003524 and FR05/11161) was developed, which has an important role in the treatment of the degenerative lumbar spine compared to conventional surgical treatment ...


Magnetic brain stimulation: calculation of electric field induced by arbitrary shaped coils in spherical coordinate with time variable

Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology, 2002

It is very important in magnetic brain stimulation that knowing the induced electric field distribution. Because of its calculation complexity, spherical coordinate is used to replace rectangular coordinate in traditional method and simplify the calculation. In this paper, the induced electric fields stimulated by arbitrary coils are calculated based on sphere head model. In the past researches, time variable was ...


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Educational Resources on Nerve tissues

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IEEE-USA E-Books

  • Micromachined Electrode Arrays with Form-Fitting Profile for Auditory Nerve Prostheses

    This paper reports the design, fabrication and simulation of a novel micromachined electrode array with a form-fitting profile for use in auditory nerve prostheses. A 10times10 electrode array is created in a 1mm<sup>2</sup> area using bulk micromachining technology. The space between the individual electrodes within the array is filled with a layer of SU-8 molded to conform to the curved surface of the auditory nerve. This layer enables the implant to be secured to the auditory nerve and to have a good sealing between the array and the nerve tissue after insertion. An electrical model for a single electrode is built. Both mechanical and electrochemical finite element analyses (FEA) of the array are also performed

  • The Measurement of Body Currents

    D.C. potentials are associated with static cellular life and are a product of metabolism. A.C. potentials are associated with many tissues controlling or responding to movement. Brain tissue is the most highly developed and exists normally in a state of constant, irregular electrical activity.

  • 6A-4 Focused Ultrasound Potential to Initiate Spreading Depression for Disruption of Blood Brain Barrier

    Blood-brain barrier (BBB) has long been known to impede the delivery of therapeutic and diagnostic agents into the central nervous system. Although ultrasound with microbubbles has been shown to disrupt the BBB, we presently examine another ultrasound-induced mechanism for opening of the BBB: ultrasound induction of spreading depression. In this process, local physical changes induced by the ultrasound pressure field, increase regional [K<sup>+</sup>]<sub>o</sub> concentration to the point of depolarization, thus initiating an oscillation process known as auto-waves or Leao spreading depression that propagates through the nerve tissue causing reversible depression of spontaneous neuronal activity. Cortical spreading depression (CSD) was induced in the brain of 18 rats by focused ultrasound (FUS) exposure (frequency: 4.89 MHz) through both the skull window (n=13) and the intact skull (n=5). CSD was also induced by application of 4 muL of 2%KCl to the cortex (n=10). Electrical activity of the cerebral cortex (ECoG) was recorded by using implanted electrodes. Occurrence of the CSD was verified through the depression of the ECoG high-frequency activity in a gamma band (&gt;20 Hz). Five to seven CSD's were initiated in each animal at the first day (electrode implantation) and induced repeatedly 1-7 days later. The CSD induced by both FUS and KCl was associated with BBB disruption detected by a leakage of trypan blue IV injected 18-20 hours after the last induced CSD. This result suggests that the FUS-induced spreading depression can be used for non-invasive BBB disruption in targeted locations. This disruption may be useful for targeted drug delivery in the brain.

  • FE Assessment of an Interspinous Implant (ISS)

    The main objective of this work is the demonstration of a conceptual approach for efficient interspinous implant evaluation and design using finite element (FE) method. A novel dynamic stabilization system (Interspinous spacer (ISS), registered in France under FR05/003524 and FR05/11161) was developed, which has an important role in the treatment of the degenerative lumbar spine compared to conventional surgical treatment -spinal fusion for chronic low back pain due to degenerative disorders in the lumbar spine. Anatomically realistic FE models of healthy, nucleotomized and implanted models of lumbar L4-L5 motion segment were exercised the physiological loading configurations under flexion, extension, lateral bending and axial rotation to investigate the biomechanical effect of the ISS by comparison of the load-response curves of the three models. Under flexion and extension, the response curves show that the range of motion of the implanted model is greatly reduced in relation to the healthy and nucleotomized models. In lateral bending mode, the response curves show that the implanted segment relative less stiff compared to the nucleotomized segment. Under axial rotation, the response curves suggests that the interspinous relatively effective in the axial rotation mode without affecting the kinematics of the L4-L5 segment. Based on the implanted L4-L5 model, the interspinous spacer has the capability of restoring back the functionality of the dissected posterior ligaments, and the kinematics of the implanted model and nucleotomized model are of similar range. The much greater stiffness of the implanted segment under sagittal bending is an issue needed to be addressed, as the motion is greatly limited.

  • Magnetic brain stimulation: calculation of electric field induced by arbitrary shaped coils in spherical coordinate with time variable

    It is very important in magnetic brain stimulation that knowing the induced electric field distribution. Because of its calculation complexity, spherical coordinate is used to replace rectangular coordinate in traditional method and simplify the calculation. In this paper, the induced electric fields stimulated by arbitrary coils are calculated based on sphere head model. In the past researches, time variable was neglected for simplification, but the electric field always varies with time. To depict it more precisely, the time variable is considered.

  • Surfactant therapy after electroporation mediated muscle injury in vivo

    High voltage electrical shock can produce extensive muscle and nerve tissue damage due to poration of cell membranes by electric field gradients in addition to thermal denaturation of biomolecules. The authors studied the therapeutic membrane sealing effect of the surfactant Poloxamer 188 on muscle tissue damage in vivo following non-thermal electrical injury in their rat hind limb model (DC-pulses, 150 V/cm) by radiotracer imaging. Poloxamer 188 surfactant injections (50 mg/kg) showed a significant decrease in radiotracer retention compared to control injections post-shock. The results indicate the importance of membrane permeabilization and the therapeutic potential of surfactant sealing in electrical shock victims.

  • Measurement of intrafascicular insertion force of a tungsten needle into peripheral nerve

    Microfabricated silicon array structures, such as those being developed by the VSAMUEL consortium may one day provide inexpensive yet highly selective chronically implanted interfaces to the peripheral nervous system. In the present study we examined the feasibility of implanting such microelectrodes into peripheral nerve tissue by characterizing the mechanical forces required for implantation. We conducted in-vitro implantation experiments into excised rabbit peripheral nerve with electrosharpened tungsten needles similar in dimension to the VSAMUEL probes. A needle was manually advanced through the epineurium and perineurium using a micro-manipulator. The force applied to the needle during the insertion process was measured using a custom built force detection device. We found that a force greater than 2 mN was necessary to insert the needle. Clear dimpling of the nerve surface was also observed prior to penetration.

  • Design of system-on-chip in 180 nm technology for multi-channel wireless recording of the nerve tissue electrical activity

    The article describes a System on Chip (SoC) for multi-channel wireless recording of nerve tissue electrical activity. Specificity of neural signals, the method of registration by using microelectrode arrays and requirements for the SoC are presented. Eventually, individual elements of the system such as conditioning module, analogue multiplexer, A/D converter, radio transmitter and system controller are discussed.

  • Application research of hypercycle theory in reverse logistics

    The academic community has found the cycle characteristics of reverse logistics while a small number of scholars studied reverse logistics from the perspective of circular economy. But few of them studied it from the perspective of hypercycle theory. In view of this, this paper, based on the hypercycle theory, analyzed the hypercycle characteristics of reverse logistics system. Then, it indicated the conditions for existence and effective operation of the hypercycle system of reverse logistics. Last, it discussed and established a hypercycle model of the reverse logistics.

  • Functional and morphological repair of rat sciatic nerve with a Hyaff11(,,Y)-based nerve guide

    Summary form only given. Biodegradable nerve guides are a good alternative for the use of autologous grafts in peripheral nerve repair. We investigated the use of a Hyaff11-based nerve guide for bridging a 1 cm gap in the rat sciatic nerve. After 7, 15, and 21 weeks, the rats were subjected to walking track analysis and withdrawal reflex tests, and the regenerated nerve tissue with surroundings was explanted and processed. Seven weeks after implantation gait analysis showed functional recovery of the hindleg. Parameters like "walking on plantair side" and "absence of dragging" already scored 100% recovery. Scoring percentage of other parameters such as "alternating steps", "normal swing phase", "hindfeet within body contour" and "fluent walking" increased in the period afterwards. The stimulus strength to evoke a pain withdrawal was 0.42 mA for the regenerated side at week 7, and this values did not decrease until 21 weeks. The control leg needed only a 0.1 mA stimulus to evoke a pain withdrawal at 7, 15, and 21 weeks. At week 7, a thin bundle of nerve tissue was formed. This bundle was however completely surrounded by (collapsed) biomaterial and a chronic foreign body reaction. The diameter of the bundle was increased at week 15 and later, but still a large amount of biomaterial was present. The Hyaff11-based nerve guide restores nerve outgrowth and function but the amount of biomaterial induces a chronic foreign body reaction which hampers the nerve repair process. A more flexible and thinner tube wall might improve the capacity of the nerve guide.



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