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The conference program will consist of plenary lectures, symposia, workshops and invitedsessions of the latest significant findings and developments in all the major fields of biomedical engineering.Submitted papers will be peer reviewed. Accepted high quality papers will be presented in oral and postersessions, will appear in the Conference Proceedings and will be indexed in PubMed/MEDLINE
IEEE International Conference on Plasma Science (ICOPS) is an annual conference coordinated by the Plasma Science and Application Committee (PSAC) of the IEEE Nuclear & Plasma Sciences Society.
INTERMAG is the premier conference on all aspects of applied magnetism and provides a range of oral and poster presentations, invited talks and symposia, a tutorial session, and exhibits reviewing the latest developments in magnetism.
The world's premiere conference in MEMS sensors, actuators and integrated micro and nano systems welcomes you to attend this four-day event showcasing major technological, scientific and commercial breakthroughs in mechanical, optical, chemical and biological devices and systems using micro and nanotechnology.The major areas of activity in the development of Transducers solicited and expected at this conference include but are not limited to: Bio, Medical, Chemical, and Micro Total Analysis Systems Fabrication and Packaging Mechanical and Physical Sensors Materials and Characterization Design, Simulation and Theory Actuators Optical MEMS RF MEMS Nanotechnology Energy and Power
Science, technology and applications spanning the millimeter-waves, terahertz and infrared spectral regions
Contains articles on the applications and other relevant technology. Electronic applications include analog and digital circuits employing thin films and active devices such as Josephson junctions. Power applications include magnet design as well asmotors, generators, and power transmission
The Transactions on Biomedical Circuits and Systems addresses areas at the crossroads of Circuits and Systems and Life Sciences. The main emphasis is on microelectronic issues in a wide range of applications found in life sciences, physical sciences and engineering. The primary goal of the journal is to bridge the unique scientific and technical activities of the Circuits and Systems ...
Specific topics of interest include, but are not limited to, sequence analysis, comparison and alignment methods; motif, gene and signal recognition; molecular evolution; phylogenetics and phylogenomics; determination or prediction of the structure of RNA and Protein in two and three dimensions; DNA twisting and folding; gene expression and gene regulatory networks; deduction of metabolic pathways; micro-array design and analysis; proteomics; ...
Theory and applications of industrial electronics and control instrumentation science and engineering, including microprocessor control systems, high-power controls, process control, programmable controllers, numerical and program control systems, flow meters, and identification systems.
Science and technology related to the basic physics and engineering of magnetism, magnetic materials, applied magnetics, magnetic devices, and magnetic data storage. The Transactions publishes scholarly articles of archival value as well as tutorial expositions and critical reviews of classical subjects and topics of current interest.
2016 IEEE 36th Central American and Panama Convention (CONCAPAN XXXVI), 2016
The advance of Molecular Nanobiotechnology grows at a fast pace and a quantity of data and biological information emerges vertiginously at a smaller scale each time. This multilateral effect, necessarily appeals to the rational design of new bioinformatics and bio computing systems, along with the structured and non-structured systematization (NoSQL) at the organization, management, processing and storage of atomic-molecular originated ...
2006 Bio Micro and Nanosystems Conference, 2006
Summary form only given. Bionanofabrication is a novel fabrication process that takes advantage of the specificity and catalytic efficiency of biological systems to create novel nanoscale structures. Polyhydroxyalkanoates (PHAs) are a family of aliphatic polyesters produced by a variety of microorganisms as a reserve of carbon and energy. PHAs can be combined from more than 100 different monomers to give ...
4th IEEE Conference on Nanotechnology, 2004., 2004
Nanobiotechnology bridges the technological gaps between physics, chemistry and biology on the nanoscale. This leads to many innovative approaches which result in new methods and products for both, technological and medical- pharmaceutical applications. This paper discusses the following question how can nanobiotechnology contribute to and combined with medical technology. Bioactive, biocompatible and functionalised surfaces are important for the further development ...
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010
The Oriented architecture of macromolecules plays a critical role in many aspects of Nanobiotechnology such as in the development of biosensors. To this regard, S-layers which constitute the outermost cell envelope component of many prokaryotic organisms, represent unique self assembled systems with the capability to rearrange into monomolecular and oriented arrays. These properties can be exploited to promote their crystallization ...
5th IEEE Conference on Nanotechnology, 2005., 2005
The relationship between nanoscience and nanotechnology is discussed in this paper. Nanobiotechnology is aimed at the molecular design of interfaces for improved medical devices and diagnostics. Medical device implants, and the biomaterials that comprise them, are measured on macro scales (centimeters). Yet the biocompatibility of such devices may be dictated by phenomena best described at nanometer dimensions. Biological data on ...
The advance of Molecular Nanobiotechnology grows at a fast pace and a quantity of data and biological information emerges vertiginously at a smaller scale each time. This multilateral effect, necessarily appeals to the rational design of new bioinformatics and bio computing systems, along with the structured and non-structured systematization (NoSQL) at the organization, management, processing and storage of atomic-molecular originated data, applied in new forms of scientific consumption, research and technology such as Big Data and Cloud communities through mobile device consulting (Apps) and Computational Biology System. Also, on the molecular nanobiotechnology applied within the medical molecular context, it is necessary to provide a clear work oriented link inside the functionality of the platform's genomic devices and integrated infrastructures as a service (SaaS, Paas, IaaS). Therefore, Bioinformatics can help and find techniques, methods and combined computing algorithms, with the object to resolve several problems and emerging actions in a hybrid integration of scientific fields. Therefore, the technological revolution and evolution on the Omics Science has had considerable advances at a parallel front through Ultra-Sequencing techniques (NGS) and high speed provisions of complete genome readings in short time and with low cost, deepening the metabolic inter-relations and unstable biological circuits in several primary attention diseases in an easier way, including the example development on this research support and through DNA nanotechnology (molecular estructure of insuline), with the object to provide immediate traslational bioinformatics services to diagnose and provide prognosis of solutions for several primary attention requirements on molecular medicine.
Summary form only given. Bionanofabrication is a novel fabrication process that takes advantage of the specificity and catalytic efficiency of biological systems to create novel nanoscale structures. Polyhydroxyalkanoates (PHAs) are a family of aliphatic polyesters produced by a variety of microorganisms as a reserve of carbon and energy. PHAs can be combined from more than 100 different monomers to give materials with widely different physical properties. PHAs are biocompatible, biodegradable and demonstrate piezo electric and non-linear optical properties making them potential useful for tissue engineering, drug delivery, degradable packaging and smart materials. The enzymes involved in the synthesis of PHAs have been harnessed in our laboratory to produce novel polymers in vitro both in bulk and on solid surfaces. Site-specific attachment of the key catalytic enzyme, PHA synthase, on nanofabricated surfaces and subsequent addition of 3-(R)-hydroxybutyryl-CoA substrates (HB-CoA), allows us to create spatially ordered polyhydroxybutyrate (PHB) polymeric structures via in situ enzymatic surface-initiated polymerization (ESIP). By varying the reaction conditions we have optimized the PHB polymer growth at the interface and the resulting material characterized by fluorescence microscopy and atomic force microscopy. In the absence of additives such as bovine serum albumin, the PHB polymer synthesized on the surfaces formed very distinct and uniform granular structures on Au patterned surfaces. The average size of PHB granules was measured to be approximately 0.5 to 1 mum in diameter and 100 nm in height from the Au surfaces. In the presence of bovine serum albumin, the average size of PHB granules and PHB film thickness significantly increased to be approximately 1 to 5 mum in diameter and 500 nm to 1 mum in height, respectively, uniformly covering patterned surfaces. We believe that the use of this novel enzymatic approach offers many practical applications in different areas. For example, it can be employed to generate biocompatible PHAs coated solid surfaces for tissue engineering, promoting cell attachment and growth. As a result, one of our goals is to employ ESIP for in situ solid-phase synthesis of novel functionalized PHAs micro-/nano- structures with a wide range of mechanical, thermal, and biocompatible properties. In addition to biocompatible surface coatings, we envision that the novel polymeric micro-/nano-structures can be built in spaces that cannot be accessed by convention lithographic tools or other fabrication process. For example, PHB structures can be formed in situ inside microfluidic channels to produce rapid microfluidic mixing. Currently, we are investigating the use of in situ synthesized PHB polymer on specific Au patterned surfaces such as straight ridges and staggered herringbone patterns to act as passive micromixers inside microfluidic channels
Nanobiotechnology bridges the technological gaps between physics, chemistry and biology on the nanoscale. This leads to many innovative approaches which result in new methods and products for both, technological and medical- pharmaceutical applications. This paper discusses the following question how can nanobiotechnology contribute to and combined with medical technology. Bioactive, biocompatible and functionalised surfaces are important for the further development of many applied medical systems like bone implants, stents and also membranes for apheresis. Furthermore nanoparticles are good candidates for establishing new therapeutic applications. They are considered and some are already applied as drug delivery systems and contrast agents. It is argued that coated nanoparticles functionalised with target molecules and interacting with eternal devices offer real perspectives for medical applications which come close to the more or less realistic visions connected with nanobots.
The Oriented architecture of macromolecules plays a critical role in many aspects of Nanobiotechnology such as in the development of biosensors. To this regard, S-layers which constitute the outermost cell envelope component of many prokaryotic organisms, represent unique self assembled systems with the capability to rearrange into monomolecular and oriented arrays. These properties can be exploited to promote their crystallization on surfaces (e.g. silicone) which is pivotal for the subsequent immobilization of macromolecules and development of new biosensors. In this work the crystallization of bacterial S-layers obtained from Bacillus thuringiensis and Bacillus sphaericus CCM2177 on silicone, mica and quartz crystal surfaces were investigated. The SDS page results of S-layers isolated from the above mentioned bacteria put in evidence that their molecular weight (MW) was around 120 KDa and, as reported in the literature, slightly higher for those extracted by Bacillus thuringiensis. In addition, results showed that S-layers isolated from Bacillus thuringiensis form large crystalline domains on mica after 5 min whereas those extracted from Bacillus sphaericus CCM 2177 form a compact monolayer on silicone after 2 h. Results in this work put in evidence the possibility to use these substrates for the fabrication of sensitive biosensors.
The relationship between nanoscience and nanotechnology is discussed in this paper. Nanobiotechnology is aimed at the molecular design of interfaces for improved medical devices and diagnostics. Medical device implants, and the biomaterials that comprise them, are measured on macro scales (centimeters). Yet the biocompatibility of such devices may be dictated by phenomena best described at nanometer dimensions. Biological data on the in vivo healing responses of mammals to matricellular proteins such as osteopontin, thrombospondin 2 and SPARC with nonspecific protein adsorption is presented. The method including protein orientation (assembly) and type I collagen used to deliver signals along with their strategies is presented. Modern surface analysis techniques shows the complexity of a functional nanobiointerface.
Nucleic acids delivered to cells are powerful research tools and promising therapeutics. Spatial and temporal control of delivery is essential for the efficacy, safety and specificity of the application. The shuttles for nucleic acid delivery, so-called vectors, are nanometric biological or synthetic entities comprising complex biological functionalities. We localize nucleic acid delivery exploiting carrier materials. These are on the one hand implantable biomaterials doted with vectors for tissue engineering purposes, on the other hand magnetic nanoparticles associated with vectors which can be magnetically directed to a target site. We pursue these approaches to provide novel tools for research and therapy.
Recently practical micro/nano devices using nanomaterials such as nanoparticles and nanowires have actively developed in various fields including nanophotonics and nanobiology. Manipulation of nanowires is indispensable for constructing the microdevices. Here we propose and experimentally demonstrates a novel method of three-dimensional optical manipulation of a metallic nanowire using an optical vortex. In our method, a metallic nanowire can be grasped by optical repulsive force and simultaneously rotated by total angular momentum of an optical vortex. In addition, the posture of a metallic nanowire can be horizontally fixed in any direction by high-speed switching of the helical phase shift of an optical vortex. A horizontally aligned nanowire can be also aligned vertically along the optical axis by gradually decreasing the size of an optical vortex focused on a tip of the nanowire. The horizontally or vertically aligned nanowire can be translated to the desired position by moving the stage supporting a sample. The manipulation technique using an optical vortex will be a powerful tool for manipulating and assembling various kinds of nanowires.
We have constructed a piezoelectric sensor matrix with the capability of measuring the flexibility of immunoglobulin. The matrix consisted of 6 independent quartz crystal microbalance (QCM) coated with gold nanoparticles (GNP) of 3.5, 5, 12, 17, and 37 nm, and BSA. The detection was performed simultaneously. Antiserum against GNP bound to QCMs coated with 3.5 nm GNP and maximized for 5 nm GNP-coated QCM. To our best knowledge, this is the first biosensor sensing the topological change and flexibility of biological macromolecule.
Nanomagnetic particles have been already taken into account as drug carriers thank to the possibility to control their movement to a specific location where the treatment is required by means of high gradient magnetic fields (HGMF). In this work the layer-by-layer technique (LbL) and nanomagnetic particles were used to developed innovative nanostructured magnetic capsules (NSMC). Their potential application as magnetic drug carriers was investigated under the influence of both static and oscillating magnetic fields used respectively to control capsule displacement and shell permeability. The assembly process of the nanostructured magnetic capsules, its characterization by Quartz Crystal Microbalance (QCM), and the results obtained under the influence of the magnetic fields are presented.
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