Conferences related to System Biology

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2023 Annual International Conference of the IEEE Engineering in Medicine & Biology Conference (EMBC)

The conference program will consist of plenary lectures, symposia, workshops and invitedsessions of the latest significant findings and developments in all the major fields of biomedical engineering.Submitted full papers will be peer reviewed. Accepted high quality papers will be presented in oral and poster sessions,will appear in the Conference Proceedings and will be indexed in PubMed/MEDLINE.


2020 59th IEEE Conference on Decision and Control (CDC)

The CDC is the premier conference dedicated to the advancement of the theory and practice of systems and control. The CDC annually brings together an international community of researchers and practitioners in the field of automatic control to discuss new research results, perspectives on future developments, and innovative applications relevant to decision making, automatic control, and related areas.


ICASSP 2020 - 2020 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP)

The ICASSP meeting is the world's largest and most comprehensive technical conference focused on signal processing and its applications. The conference will feature world-class speakers, tutorials, exhibits, and over 50 lecture and poster sessions.


IECON 2020 - 46th Annual Conference of the IEEE Industrial Electronics Society

IECON is focusing on industrial and manufacturing theory and applications of electronics, controls, communications, instrumentation and computational intelligence.


2019 IEEE SENSORS

The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state-of-the art information including the latest research and development in sensors and their related fields. It brings together researchers, developers, and practitioners from diverse fields including international scientists and engineers from academia, research institutes, and companies to present and discuss the latest results in the general field of sensors.

  • 2018 IEEE SENSORS

    The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state -of-the art information including the latest research and development in sensors and their relatedfields. It brings together researchers, developers, and practitioners from diverse fields includinginternational scientists and engineers from academia, research institutes, and companies topresent and discuss the latest results in the general field of sensors.

  • 2017 IEEE SENSORS

    The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state -of-the art information including the latest research and development in sensors and their relatedfields. It brings together researchers, developers, and practitioners from diverse fields includinginternational scientists and engineers from academia, research institutes, and companies topresent and discuss the latest results in the general field of sensors.

  • 2016 IEEE Sensors

    The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state -of-the art information including the latest research and development in sensors and their related fields. It brings together researchers, developers, and practitioners from diverse fields including international scientists and engineers from academia, research institutes, and companies to present and discuss the latest results in the general field of sensors.

  • 2015 IEEE Sensors

    The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state -of-the art information including the latest research and development in sensors and their related fields. It brings together researchers, developers, and practitioners from diverse fieldsincluding international scientists and engineers from academia, research institutes, and companies topresent and discuss the latest results in the general field of sensors.

  • 2014 IEEE Sensors

    The IEEE Sensors Conference is a forum for presentation, discussion, andexchange of state -of-the art information including the latest research and development in sensors andtheir related fields. It brings together researchers, developers, and practitioners from diverse fieldsincluding international scientists and engineers from academia, research institutes, and companies topresent and discuss the latest results in the general field of sensors.

  • 2013 IEEE Sensors

    The IEEE SENSORS Conference is a forum for presentation, discussion, and exchange of state -of-the art information including the latest research and development in sensors and their related fields. It brings together researchers, developers, and practitioners from diverse fields including international scientists and engineers from academia, research institutes, and companies to present and discuss the latest results in the general field of sensors.

  • 2012 IEEE Sensors

    The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state-of-the art information including the latest research and development in sensors and their related fields. It brings together researchers, developers, and practitioners from diverse fields including international scientists and engineers from academia, research institutes, and companies to present and discuss the latest results in the general field of sensors.

  • 2011 IEEE Sensors

    The IEEE Sensors Conference is a forum for presentation, discussion, and exchange of state-of-the art information including the latest research and development in sensors and their related fields. It brings together researchers, developers, and practitioners from diverse fields including international scientists and engineers from academia, research institutes, and companies to present and discuss the latest results in the general field of sensors. IEEE SENSORS 2011 will include keynote addresses by eminen

  • 2010 IEEE Sensors

    The IEEE SENSORS 2010 Conference is a forum for state-of-the-art presentations on sensors and related topics covering from theory to application, device to system, modeling to implementation and from macro/nano to scale.

  • 2009 IEEE Sensors

    IEEE Sensors Conference 2009 is intended to provide a common forum for researchers, scientists, engineers and practitioners throughout the world to present their latest research findings, ideas, developments and applications in the area of sensors and sensing technology. IEEE Sensors Conference 2009 will include keynote addresses by eminent scientists as well as special, regular and poster sessions.

  • 2008 IEEE Sensors

    IEEE SENSORS 2008 solicits original and state-of-the-art contributions to sensors and related topics, covering from theory to application, from device to system, from modeling to implementation, and from macro to micro/nano in scale. Topics of interest include,but are not limitid to: Phenomena, Modeling, and Evaluation (Novel Sensing Principles, Theory and Modeling, Sensors Characterization, Evaluation and Testing, Data Handling and Mining) Chemical and Gas Sensors (Materials, Devices, Electronics N

  • 2007 IEEE Sensors

    IEEE SENSORS 2007 solicits original and state-of-the-art contributions to sensors and related topics, covering from theory to application, from device to system, from modeling to implementation, and from macro to micro/nano in scale.

  • 2006 IEEE Sensors

  • 2005 IEEE Sensors

  • 2004 IEEE Sensors

  • 2003 IEEE Sensors

  • 2002 IEEE Sensors


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Periodicals related to System Biology

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Automatic Control, IEEE Transactions on

The theory, design and application of Control Systems. It shall encompass components, and the integration of these components, as are necessary for the construction of such systems. The word `systems' as used herein shall be interpreted to include physical, biological, organizational and other entities and combinations thereof, which can be represented through a mathematical symbolism. The Field of Interest: shall ...


Biomedical Circuits and Systems, IEEE Transactions on

The Transactions on Biomedical Circuits and Systems addresses areas at the crossroads of Circuits and Systems and Life Sciences. The main emphasis is on microelectronic issues in a wide range of applications found in life sciences, physical sciences and engineering. The primary goal of the journal is to bridge the unique scientific and technical activities of the Circuits and Systems ...


Biomedical Engineering, IEEE Reviews in

The IEEE Reviews in Biomedical Engineering will review the state-of-the-art and trends in the emerging field of biomedical engineering. This includes scholarly works, ranging from historic and modern development in biomedical engineering to the life sciences and medicine enabled by technologies covered by the various IEEE societies.


Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


Circuits and Systems I: Regular Papers, IEEE Transactions on

Part I will now contain regular papers focusing on all matters related to fundamental theory, applications, analog and digital signal processing. Part II will report on the latest significant results across all of these topic areas.


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Most published Xplore authors for System Biology

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Xplore Articles related to System Biology

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Modeling and simulation analysis of Salmonella typhimurium inside human epithelial cells: Host-pathogen relationship analysis by system biology

2016 International Conference on Bioinformatics and Systems Biology (BSB), 2016

Bacteria have the tendency to acquire resistance and develop defense from drug which makes pharmaceutical industries to work and develop new strategies for producing effective antibiotics against them. With molecular advancement and better understanding to their pathway architecture, channel for developing better antibiotics is open. Here we try to understand the enzyme kinetics of each protein and system biology of ...


The Logic of Hypothesis Generation in Kinetic Modeling of System Biology

2011 IEEE 23rd International Conference on Tools with Artificial Intelligence, 2011

In the past decades a lot of researches have been conducted to investigate pathways in order to increase the understanding of the mechanisms responsible for diseases and thus to find new treatments. One strategy to achieve this goal would be to inhibit or to trigger a part of the pathway that produces the disease. A strategy would be to first ...


A system biology approach to robustness analysis of circadian rhythm

First International Symposium on Control, Communications and Signal Processing, 2004., 2004

Summary form only given. Understanding regulation is a critical hurdle in unraveling complex biological systems. As gene-level architectures become known, the open challenge is to assign predictable behavior to a known structure, the so-called "genotype-to-phenotype" problem. In response to this challenge, the discipline of systems biology has emerged with an integrative perspective towards determining complex systems behavior. A property of ...


Benchmarking Dependability of a System Biology Application

2009 14th IEEE International Conference on Engineering of Complex Computer Systems, 2009

In this paper we report our practical experience in benchmarking a System Biology Web Service, and investigate instability of its performance and the delays induced by the communication medium. We discuss the results of a statistical data analysis and discuss the causes affecting the Web Service performance. The uncertainty discovered in Web Services operations reduces the overall dependability of Service-Oriented ...


A multiscale, model-based analysis of the multi-tissue interplay underlying blood glucose regulation in type I diabetes

2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2016

A multiscale model for blood glucose regulation in diabetes type I patients is constructed by integrating detailed metabolic network models for fat, liver and muscle cells into a whole body physiologically-based pharmacokinetic/pharmacodynamic (pBPK/PD) model. The blood glucose regulation PBPK/PD model simulates the distribution and metabolization of glucose, insulin and glucagon on an organ and whole body level. The genome-scale metabolic ...


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Educational Resources on System Biology

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IEEE-USA E-Books

  • Modeling and simulation analysis of Salmonella typhimurium inside human epithelial cells: Host-pathogen relationship analysis by system biology

    Bacteria have the tendency to acquire resistance and develop defense from drug which makes pharmaceutical industries to work and develop new strategies for producing effective antibiotics against them. With molecular advancement and better understanding to their pathway architecture, channel for developing better antibiotics is open. Here we try to understand the enzyme kinetics of each protein and system biology of Salmonella typhi and infected host cell by its virulence factors. With taking in consideration, we have identified expressed protein CDC42, HiLD, and Arp2/3 complex protein in disease state when pathogen attacks the host. This study opens target for developing future drugs against salmonella typhi infection.

  • The Logic of Hypothesis Generation in Kinetic Modeling of System Biology

    In the past decades a lot of researches have been conducted to investigate pathways in order to increase the understanding of the mechanisms responsible for diseases and thus to find new treatments. One strategy to achieve this goal would be to inhibit or to trigger a part of the pathway that produces the disease. A strategy would be to first identify the pathway whose activity contributes to the disease and then look for drugs that inhibit or trigger the pathway acting on its internal components and reactions.

  • A system biology approach to robustness analysis of circadian rhythm

    Summary form only given. Understanding regulation is a critical hurdle in unraveling complex biological systems. As gene-level architectures become known, the open challenge is to assign predictable behavior to a known structure, the so-called "genotype-to-phenotype" problem. In response to this challenge, the discipline of systems biology has emerged with an integrative perspective towards determining complex systems behavior. A property of particular interest is the robustness of the biophysical network: the ability to maintain some target level of behavior or performance in the presence of uncertainty and/or perturbations. In biological systems, these disturbances can be environmental (heat, pH, etc.) or intrinsic to the organism (changes in kinetic parameters). While preliminary results are available for simple (low- dimensional, deterministic) biological systems, general tools for analyzing these tradeoffs are the subject of active research. The gene network which underlies circadian rhythms is an ideal system for robustness studies, owing to its remarkable performance in a highly uncertain environment. Of interest for control theoretic analyses, the dominant elements of the postulated architecture for Drosophila consist of nested negative autoregulatory feedback loops controlling the expression of timeless (tim) and period (per) interlocked with a positive feedback loop established via the dClock gene. Complex formation, regulated translocation and degradation of several of these gene products, which is additionally controlled (and delayed) by protein phosphorylation, add further levels of complexity to the system. In this talk, a number of quantitative tools from systems theory are presented as enabling methodologies for unraveling robust biological regulatory systems, with an emphasis on sensitivity analysis. Our work on modeling and analysis of the Drosophila circadian rhythm gene network are detailed, and generalizations are be drawn for the mammalian analog and for more general gene regulatory networks.

  • Benchmarking Dependability of a System Biology Application

    In this paper we report our practical experience in benchmarking a System Biology Web Service, and investigate instability of its performance and the delays induced by the communication medium. We discuss the results of a statistical data analysis and discuss the causes affecting the Web Service performance. The uncertainty discovered in Web Services operations reduces the overall dependability of Service-Oriented Architecture and require specific resilience techniques.

  • A multiscale, model-based analysis of the multi-tissue interplay underlying blood glucose regulation in type I diabetes

    A multiscale model for blood glucose regulation in diabetes type I patients is constructed by integrating detailed metabolic network models for fat, liver and muscle cells into a whole body physiologically-based pharmacokinetic/pharmacodynamic (pBPK/PD) model. The blood glucose regulation PBPK/PD model simulates the distribution and metabolization of glucose, insulin and glucagon on an organ and whole body level. The genome-scale metabolic networks in contrast describe intracellular reactions. The developed multiscale model is fitted to insulin, glucagon and glucose measurements of a 48h clinical trial featuring 6 subjects and is subsequently used to simulate (in silico) the influence of geneknockouts and drug-induced enzyme inhibitions on whole body blood glucose levels. Simulations of diabetes associated gene knockouts and impaired cellular glucose metabolism, resulted in elevated whole body blood-glucose levels, but also in a metabolic shift within the cell's reaction network. Such multiscale models have the potential to be employed in the exploration of novel drug-targets or to be integrated into control algorithms for artificial pancreas systems.

  • Two-Photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement

    Small molecule therapeutic drugs must reach their intended cellular targets (pharmacokinetics) and engage them to modulate therapeutic effects (pharmacodynamics). These processes are often difficult to measure in vivo due to their complexities and occurrence within single cells. It has been particularly difficult to directly measure cellular drug target binding. Fluorescence polarization is commonly used in pharmacological screening assays to measure drug-protein or protein-protein interactions. We hypothesized that fluorescence polarization imaging could be adapted and used with fluorescently labeled drugs to measure drug target engagement in vivo . Here, we summarize recent results using two photon fluorescence anisotropy microscopy. Our imaging technique offers quantitative pharmacological binding information of diverse molecular interactions at the microscopic level, differentiating between bound, and unbound states. Used in combination with other recent advances in the development of novel fluorescently labeled drugs, we expect that the described imaging modality will provide a window into the distribution and efficacy of drugs in real time and in vivo at the cellular and subcellular level.

  • Advanced Motion Compensation Methods for Intravital Optical Microscopy

    Intravital microscopy has emerged in the recent decade as an indispensible imaging modality for the study of the microdynamics of biological processes in live animals. Technical advancements in imaging techniques and hardware components, combined with the development of novel targeted probes and new mice models, have enabled us to address long-standing questions in several biology areas such as oncology, cell biology, immunology, and neuroscience. As the instrument resolution has increased, physiological motion activities have become a major obstacle that prevents imaging live animals at resolutions analogue to the ones obtained in vitro. Motion compensation techniques aim at reducing this gap and can effectively increase the in vivo resolution. This paper provides a technical review of some of the latest developments in motion compensation methods, providing organ specific solutions.

  • Synchronization control for circadian rhythm of drosophila with flatness-based adaptive control

    Developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.

  • Design of periodic control systems for circadian rhythm of mammals

    Recently, developing molecular biology and system biology, the mechanism of the circadian rhythm in which the inside of the body rhythm of the living thing is ruled is being clarified at the cell level. On the other hand, it is said that various sicknesses are related in the medicine and pharmacology to the disorder of the circadian rhythm. Therefore, it is thought that to restore an altered rhythm is a goal of these therapies. In this paper, we study the 10-states circadian model of Drosophila and propose a close-loop control based on flatness-based adaptive control to achieve circadian rhythm restoration.

  • Main steam pressure control system based on two-cell immune mechanism in power plant

    The main steam pressure control system in power plant is adjusted by the variation of the fuel quantity and give-wind. It is a large inertia, long time-delay system relative to the variation of fuel. Conventional PID cascade control system canpsilat obtain satisfied control performance due to the time- delay characteristic of main steam pressure system which is incarnated mainly on the steam-water system. Biology immune system has strong robustness and self-adaptability even when encountering a great deal of disturbances and uncertain conditions. Aiming at the large inertia and long time-delay characteristics of the main steam pressure system and prompted by the two-cell immune feedback mechanism model of biology system, a new control strategy of the main steam pressure control system based on two-cell immune feedback mechanism which uses the furnace radiant energy as middle adjustment signal is presented in this paper. Simulation results show that the control strategy can achieve satisfied control performance and has strong robustness, self- adaptability and disturbance rejection ability.



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