Conferences related to Molecular Biology

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2021 IEEE Pulsed Power Conference (PPC)

The Pulsed Power Conference is held on a biannual basis and serves as the principal forum forthe exchange of information on pulsed power technology and engineering.


2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

The conference program will consist of plenary lectures, symposia, workshops and invitedsessions of the latest significant findings and developments in all the major fields of biomedical engineering.Submitted papers will be peer reviewed. Accepted high quality papers will be presented in oral and postersessions, will appear in the Conference Proceedings and will be indexed in PubMed/MEDLINE


2020 57th ACM/ESDA/IEEE Design Automation Conference (DAC)

The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2022 59th ACM/ESDA/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2021 58th ACM/ESDA/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2019 56th ACM/ESDA/IEEE Design Automation Conference (DAC)

    EDA (Electronics Design Automation) is becoming ever more important with the continuous scaling of semiconductor devices and the growing complexities of their use in circuits and systems. Demands for lower-power, higher-reliability and more agile electronic systems raise new challenges to both design and design automation of such systems. For the past five decades, the primary focus of research track at DAC has been to showcase leading-edge research and practice in tools and methodologies for the design of circuits and systems.

  • 2018 55th ACM/ESDA/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2017 54th ACM/EDAC/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2016 53nd ACM/EDAC/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2015 52nd ACM/EDAC/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2014 51st ACM/EDAC/IEEE Design Automation Conference (DAC)

    DAC Description for TMRF The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 sessions on design methodologies and EDA tool developments, keynotes, panels, plus the NEW User Track presentations. A diverse worldwide community representing more than 1,000 organizations attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading

  • 2013 50th ACM/EDAC/IEEE Design Automation Conference (DAC)

    The world's premier EDA and semiconductor design conference and exhibition. DAC features over 60 session on design methodologies and EDA tool developments, keynotes, panels, plus User Track presentations. A diverse worldwide community representing more than 1,000 organization attends each year, from system designers and architects, logic and circuit designers, validation engineers, CAD managers, senior managers and executives to researchers and academicians from leading universities.

  • 2012 49th ACM/EDAC/IEEE Design Automation Conference (DAC)

    The Design Automation Conference (DAC) is the premier event for the design of electronic circuits and systems, and for EDA and silicon solutions. DAC features a wide array of technical presentations plus over 200 of the leading electronics design suppliers

  • 2011 48th ACM/EDAC/IEEE Design Automation Conference (DAC)

    The Design Automation Conference is the world s leading technical conference and tradeshow on electronic design and design automation. DAC is where the IC Design and EDA ecosystem learns, networks, and does business.

  • 2010 47th ACM/EDAC/IEEE Design Automation Conference (DAC)

    The Design Automation Conference (DAC) is the premier event for the design of electronic circuits and systems, and for EDA and silicon solutions. DAC features a wide array of technical presentations plus over 200 of the leading electronics design suppliers.

  • 2009 46th ACM/EDAC/IEEE Design Automation Conference (DAC)

    DAC is the premier event for the electronic design community. DAC offers the industry s most prestigious technical conference in combination with the biggest exhibition, bringing together design, design automation and manufacturing market influencers.

  • 2008 45th ACM/EDAC/IEEE Design Automation Conference (DAC)

    The Design Automation Conference (DAC) is the premier event for the design of electronic circuits and systems, and for EDA and silicon solutions. DAC features a wide array of technical presentations plus over 250 of the leading electronics design suppliers.

  • 2007 44th ACM/IEEE Design Automation Conference (DAC)

    The Design Automation Conference (DAC) is the premier Electronic Design Automation (EDA) and silicon solution event. DAC features over 50 technical sessions covering the latest in design methodologies and EDA tool developments and an Exhibition and Demo Suite area with over 250 of the leading EDA, silicon and IP Providers.

  • 2006 43rd ACM/IEEE Design Automation Conference (DAC)

  • 2005 42nd ACM/IEEE Design Automation Conference (DAC)

  • 2004 41st ACM/IEEE Design Automation Conference (DAC)

  • 2003 40th ACM/IEEE Design Automation Conference (DAC)

  • 2002 39th ACM/IEEE Design Automation Conference (DAC)

  • 2001 38th ACM/IEEE Design Automation Conference (DAC)

  • 2000 37th ACM/IEEE Design Automation Conference (DAC)

  • 1999 36th ACM/IEEE Design Automation Conference (DAC)

  • 1998 35th ACM/IEEE Design Automation Conference (DAC)

  • 1997 34th ACM/IEEE Design Automation Conference (DAC)

  • 1996 33rd ACM/IEEE Design Automation Conference (DAC)


2020 59th IEEE Conference on Decision and Control (CDC)

The CDC is the premier conference dedicated to the advancement of the theory and practice of systems and control. The CDC annually brings together an international community of researchers and practitioners in the field of automatic control to discuss new research results, perspectives on future developments, and innovative applications relevant to decision making, automatic control, and related areas.


2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI 2020)

The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2020 will be the 17th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2020 meeting will continue this tradition of fostering cross-fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging.ISBI 2019 will be the 16th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2019 meeting will continue this tradition of fostering cross fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2018 will be the 15th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2018 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2017 will be the 14th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2017 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI 2016)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forumfor the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2016 willbe the thirteenth meeting in this series. The previous meetings have played a leading role in facilitatinginteraction between researchers in medical and biological imaging. The 2016 meeting will continue thistradition of fostering crossfertilization among different imaging communities and contributing to an integrativeapproach to biomedical imaging across all scales of observation.

  • 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI 2015)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2015 will be the 12th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2014 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI 2014)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2014 will be the eleventh meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2014 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2013 IEEE 10th International Symposium on Biomedical Imaging (ISBI 2013)

    To serve the biological, biomedical, bioengineering, bioimaging and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012)

    To serve the biological, biomedical, bioengineering, bioimaging, and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2011 IEEE 8th International Symposium on Biomedical Imaging (ISBI 2011)

    To serve the biological, biomedical, bioengineering, bioimaging, and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2010 IEEE 7th International Symposium on Biomedical Imaging (ISBI 2010)

    To serve the biological, biomedical, bioengineering, bioimaging, and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2009 IEEE 6th International Symposium on Biomedical Imaging (ISBI 2009)

    Algorithmic, mathematical and computational aspects of biomedical imaging, from nano- to macroscale. Topics of interest include image formation and reconstruction, computational and statistical image processing and analysis, dynamic imaging, visualization, image quality assessment, and physical, biological and statistical modeling. Molecular, cellular, anatomical and functional imaging modalities and applications.

  • 2008 IEEE 5th International Symposium on Biomedical Imaging (ISBI 2008)

    Algorithmic, mathematical and computational aspects of biomedical imaging, from nano- to macroscale. Topics of interest include image formation and reconstruction, computational and statistical image processing and analysis, dynamic imaging, visualization, image quality assessment, and physical, biological and statistical modeling. Molecular, cellular, anatomical and functional imaging modalities and applications.

  • 2007 IEEE 4th International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2007)

  • 2006 IEEE 3rd International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2006)

  • 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2004)

  • 2002 1st IEEE International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2002)


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Periodicals related to Molecular Biology

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Automatic Control, IEEE Transactions on

The theory, design and application of Control Systems. It shall encompass components, and the integration of these components, as are necessary for the construction of such systems. The word `systems' as used herein shall be interpreted to include physical, biological, organizational and other entities and combinations thereof, which can be represented through a mathematical symbolism. The Field of Interest: shall ...


Biomedical Circuits and Systems, IEEE Transactions on

The Transactions on Biomedical Circuits and Systems addresses areas at the crossroads of Circuits and Systems and Life Sciences. The main emphasis is on microelectronic issues in a wide range of applications found in life sciences, physical sciences and engineering. The primary goal of the journal is to bridge the unique scientific and technical activities of the Circuits and Systems ...


Biomedical Engineering, IEEE Reviews in

The IEEE Reviews in Biomedical Engineering will review the state-of-the-art and trends in the emerging field of biomedical engineering. This includes scholarly works, ranging from historic and modern development in biomedical engineering to the life sciences and medicine enabled by technologies covered by the various IEEE societies.


Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


Computational Biology and Bioinformatics, IEEE/ACM Transactions on

Specific topics of interest include, but are not limited to, sequence analysis, comparison and alignment methods; motif, gene and signal recognition; molecular evolution; phylogenetics and phylogenomics; determination or prediction of the structure of RNA and Protein in two and three dimensions; DNA twisting and folding; gene expression and gene regulatory networks; deduction of metabolic pathways; micro-array design and analysis; proteomics; ...


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Most published Xplore authors for Molecular Biology

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Xplore Articles related to Molecular Biology

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The Application of Sandwich Method in Experimental Teaching of Molecular Biology Based on qPCR Technology

2018 9th International Conference on Information Technology in Medicine and Education (ITME), 2018

Experimental teaching is an important part in the cultivation of molecular biology majors or relevant professionals. It is very necessary to develop comprehensive exploratory experiments to improve the quality of molecular biology experiment teaching. Applying Quantitative Real-time PCR (qPCR) as core technology and “Sandwich teaching method” in lesson delivery, we opened an exploratory experimental course on molecular biology for postgraduate ...


Communication theory and molecular biology at the crossroads

IEEE Engineering in Medicine and Biology Magazine, 2006

This paper endeavors to explore ideas at the crossroads of communication theory and molecular biology from various disciplinary backgrounds and vantage points, providing an overview of the state of research and making compelling observations regarding the nature of biological information transmission in light of the principles of digital communication. The paper also focuses on whether evidence of coding theoretic properties ...


Tangible augmented interfaces for structural molecular biology

IEEE Computer Graphics and Applications, 2005

With the prevalence of structural and genomic data, molecular biology has become a human-guided, computer-assisted endeavor. The computer assists the essential human function in two ways: For exploring scientific data, it searches for and tests scientific hypotheses. For collaborating between two or more scientists, it shares knowledge and expertise. As databases grow, as structure and process models become more complex, ...


Research on Anatomy and Molecular Biology of Choiromyces Helanshanensis in Inner Mongolia

2018 9th International Conference on Information Technology in Medicine and Education (ITME), 2018

the samples collected in the Helan Mountain of Inner Mongolia were studied by Anatomy and molecular biology and found that strain of ascoma was tan, smooth surface, no obvious verrucous protuberance and edges. Gleba of strains was brown, dense, and ivory of vagus veins; Spherical or rodshaped ascus in honeycomb arrangement contained 1-4 ascospore with package; the surface of ascospore ...


Systems Theoretic Analysis of the Central Dogma of Molecular Biology: Some Recent Results

IEEE Transactions on NanoBioscience, 2010

This paper extends our early study on a mathematical formulation of the central dogma of molecular biology, and focuses discussions on recent insights obtained by employing advanced systems theoretic analysis. The goal of this paper is to mathematically represent and interpret the genetic information flow at the molecular level, and explore the fundamental principle of molecular biology at the system ...


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Educational Resources on Molecular Biology

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IEEE.tv Videos

EMBC 2011-Program-Systems in Synthetic Biology (Part I)-Bruce Tidor
EMBC 2011-Keynote Lectures and Panel Discussion-PT I-Subra Suresh
Synthetic Biology: Gene Editing’s Role in Diagnostics - Andrew Ellington - IEEE EMBS at NIH, 2019
Q&A with Jo Jo Platt, IEEE Brain Podcast, Episode 14
Molecular Diagnostics for STIs - Gary Schoolnik - IEEE EMBS at NIH, 2019
ICASSP 2010 - Advances in Neural Engineering
Unmet Needs for POC Technology: HIV/AIDS - Ronald Collman - IEEE EMBS at NIH, 2019
POC AAT-based Diagnostic Technology - Paul Yager - IEEE EMBS at NIH, 2019
Unmet Needs in the Diagnosis and Management of TB - Richard Chaisson - IEEE EMBS at NIH, 2019
Long & Winding Road From Technology to Products - Keynote David Alland - IEEE EMBS at NIH, 2019
Panel: Unmet Needs in HIV/AIDS & TB Diagnosis & Management - IEEE EMBS at NIH, 2019
Paper & Microfluidic Systems for Infectious Disease Diagnostics - Catherine Klapperich - IEEE EMBS at NIH, 2019
Molecular Cellular Networks: A Non von Neumann Architecture for Molecular Electronics - Craig Lent: 2016 International Conference on Rebooting Computing
From Biology to Robot and Back
Larson Collection interview with Melvin Calvin
EMBC 2011-Program-Systems in Synthetic Biology (Part I)-Pamela A. Silver
Part Two: Interview with John Tisdale—IEEE VIC Summit 2018
EMBC 2011-Workshop-Nanobiomaterials-Ehsan Jabbarzadeh
IMS 2015 Keynote: The Century of Biology is Great for Engineering
EMBC 2011-Workshop-Nanobiomaterials-Ali Khademhosseini

IEEE-USA E-Books

  • The Application of Sandwich Method in Experimental Teaching of Molecular Biology Based on qPCR Technology

    Experimental teaching is an important part in the cultivation of molecular biology majors or relevant professionals. It is very necessary to develop comprehensive exploratory experiments to improve the quality of molecular biology experiment teaching. Applying Quantitative Real-time PCR (qPCR) as core technology and “Sandwich teaching method” in lesson delivery, we opened an exploratory experimental course on molecular biology for postgraduate students. This article described the objectives of the course, the design of content, program arrangement and so on, discussed the application and effect of Sandwich teaching method in molecular biology teaching. The results showed that this experimental item not only can leverage understanding the theoretical knowledge of molecular biology, but also efficiently improve the subjective initiative of postgraduate students, is beneficial to cultivate the ability of systematical analysis and scientific research.

  • Communication theory and molecular biology at the crossroads

    This paper endeavors to explore ideas at the crossroads of communication theory and molecular biology from various disciplinary backgrounds and vantage points, providing an overview of the state of research and making compelling observations regarding the nature of biological information transmission in light of the principles of digital communication. The paper also focuses on whether evidence of coding theoretic properties exists in biology and if such evidence supports information or coding theory view of genetics. The successful development of biological information and coding can provide a theoretical basis for understanding, quantifying, and engineering error control in natural and synthesized biosystems. The intersection of communication theory and molecular biology could potentially yield a quantitative framework for engineering fault-tolerant genes, proteins, and genomes that approach an organism's communication capacity. Immediate applications of coding theory and coding theoretic principles to genomics are presented.

  • Tangible augmented interfaces for structural molecular biology

    With the prevalence of structural and genomic data, molecular biology has become a human-guided, computer-assisted endeavor. The computer assists the essential human function in two ways: For exploring scientific data, it searches for and tests scientific hypotheses. For collaborating between two or more scientists, it shares knowledge and expertise. As databases grow, as structure and process models become more complex, and as software methods become more diverse, access and manipulation of digital information is increasingly a critical issue for research and collaboration in molecular biology. We have developed an augmented reality (AR) system that lets virtual 3D representations of molecular structures and properties be overlaid on autofabricated models of the molecules. While using our tangible interaction environment, users can intuitively manipulate molecular models and interactions, easily change the representation shown, and access information about molecular properties.

  • Research on Anatomy and Molecular Biology of Choiromyces Helanshanensis in Inner Mongolia

    the samples collected in the Helan Mountain of Inner Mongolia were studied by Anatomy and molecular biology and found that strain of ascoma was tan, smooth surface, no obvious verrucous protuberance and edges. Gleba of strains was brown, dense, and ivory of vagus veins; Spherical or rodshaped ascus in honeycomb arrangement contained 1-4 ascospore with package; the surface of ascospore had a protuberant ornamentation and was spherical. Thickness of double wall was about 1.7μm. Diameter of ascospore was 20 microns (including ascospore grain). The molecular evolution analysis shows that the strain was Choiromyces helanshanensis.

  • Systems Theoretic Analysis of the Central Dogma of Molecular Biology: Some Recent Results

    This paper extends our early study on a mathematical formulation of the central dogma of molecular biology, and focuses discussions on recent insights obtained by employing advanced systems theoretic analysis. The goal of this paper is to mathematically represent and interpret the genetic information flow at the molecular level, and explore the fundamental principle of molecular biology at the system level. Specifically, group theory was employed to interpret concepts and properties of gene mutation, and predict backbone torsion angle along the peptide chain. Finite state machine theory was extensively applied to interpret key concepts and analyze the processes related to DNA hybridization. Using the proposed model, we have transferred the character-based model in molecular biology to a sophisticated mathematical model for calculation and interpretation.

  • Replication and Update of Molecular Biology Databases

    Update of molecular biology databases is a growing burden on the biomedical research community. As the grid allows to share and replicate data, we propose a service to automatically update the molecular biology databases from a single changing reference using Web services. In this paper we report the components, the architecture, and the deployment of the update service on the french RUGBI grid infrastructure. RUGBI is a computing grid infrastructure based on existing middleware and technologies for the community of scientists in bioinformatics.

  • A new gene expression signature related to breast cancer estrogen receptor status

    The aim of this study is to identify a gene expression signature which is characteristic of ER status in breast cancer patients. To our knowledge, this is the first microarray study in Greece involving clinical samples. We identified 97 genes that are characteristic for ER status and can well distinguish the ER+ from the ER- samples. We shrank our list to a 11-gene list correlating to the same patient ER status. We found a significant overlap of these genes with published ER status characteristic signatures like the ones of West et.al. and of Vanpsilat Veer et. al.. This fact is very important given the minimal overlap of such genes reported by others . In order to obtain a molecular insight into how the expression of estrogen receptor activates cancer cells, we found associations with biological pathways. Interestingly, the vast majority of these genes are highly related to breast cancer.

  • A Generic Architectural Framework for Proactive Systems Inspired by Molecular Biology

    A generic framework for the development of proactive systems inspired by molecular biology systems is presented in this paper. Proactive systems need to predict future concerns and not only finding solutions to problems as is the case with conventional systems. The framework is also generic enough to represent human behaviour in general. It is also applicable to conventional systems. The main feature of the proposed framework is that allows the incorporation of all possible frameworks and findings about a subject matter into one fused framework.

  • Structural mining of molecular biology data

    One method for discovering knowledge in structural data is the identification of common substructures, or subgraphs, within the data. Once identified, these substructures can be used to simplify the data by replacing instances of the substructure with a pointer to the newly discovered concept. The discovered substructure concepts allow abstraction over detailed structure in the original data and provide new, relevant attributes for interpreting the data. In this article, we describe the SUBDUE system that discovers interesting substructures in structural data. SUBDUE discovers substructures that compress the original database and represent interesting structural concepts in the data. By compressing previously discovered substructures in the data, multiple passes of SUBDUE produce a hierarchical description of the structural regularities in the data, The capabilities of SUBDUE are used to discover patterns in protein and DNA databases.

  • Implementing an integrated system for heterogeneous molecular biology databases with intelligent agents

    We propose a method for integrating heterogeneous molecular biology databases. Since molecular biology data are distributed among multiple repositories that represent different biological domains, it is useful to integrate data along with the correlations of the domains. In our method, the integration is dynamically carried out by two types of agents; database agent and user agent, which reside at a data repository and a user, respectively. By limiting the search space with keywords specified by users, the cost of integration can be reduced considerably. The performance of a prototype system was evaluated by measuring the execution time for integration of GenBank (a DNA nucleotide database), SWISS-PROT, PIR (protein amino-acid sequence databases) and PDB (a protein 3D structure database) with a sample query.



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