96 resources related to Cartilage
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IEEE International Conference on Plasma Science (ICOPS) is an annual conference coordinated by the Plasma Science and Application Committee (PSAC) of the IEEE Nuclear & Plasma Sciences Society.
To promote awareness, understanding, advancement and application of ocean engineering and marine technology. This includes all aspects of science, engineering, and technology that address research, development, and operations pertaining to all bodies of water. This includes the creation of new capabilities and technologies from concept design through prototypes, testing, and operational systems to sense, explore, understand, develop, use, and responsibly manage natural resources.
The world's premiere conference in MEMS sensors, actuators and integrated micro and nano systems welcomes you to attend this four-day event showcasing major technological, scientific and commercial breakthroughs in mechanical, optical, chemical and biological devices and systems using micro and nanotechnology.The major areas of activity in the development of Transducers solicited and expected at this conference include but are not limited to: Bio, Medical, Chemical, and Micro Total Analysis Systems Fabrication and Packaging Mechanical and Physical Sensors Materials and Characterization Design, Simulation and Theory Actuators Optical MEMS RF MEMS Nanotechnology Energy and Power
The conference program will consist of plenary lectures, symposia, workshops andinvitedsessions of the latest significant findings and developments in all the major fields ofbiomedical engineering.Submitted papers will be peer reviewed. Accepted high quality paperswill be presented in oral and postersessions, will appear in the Conference Proceedings and willbe indexed in PubMed/MEDLINE & IEEE Xplore
The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging.ISBI 2019 will be the 16th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2019 meeting will continue this tradition of fostering cross fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.
Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.
Both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence. Special interest departments, students, law, clinical engineering, ethics, new products, society news, historical features and government.
Telemedicine, teleradiology, telepathology, telemonitoring, telediagnostics, 3D animations in health care, health information networks, clinical information systems, virtual reality applications in medicine, broadband technologies, and global information infrastructure design for health care.
The IEEE Region 9 is releasing the IEEE Latin America Transactions to enable the publication of non-published and technically excellent papers from Latin American engineers, in Spanish or Portuguese languages. Engineers and researchers from Portugal and Spain (and others countries with the same language) are also very welcome to submit their proposals.
Synergetic integration of mechanical engineering with electronic and intelligent computer control in the design and manufacture of industrial products and processes. (4) (IEEE Guide for Authors) A primary purpose is to have an aarchival publication which will encompass both theory and practice. Papers will be published which disclose significant new knowledge needed to implement intelligent mechatronics systems, from analysis and ...
LEOS '92 Conference Proceedings, 1992
2012 38th Annual Northeast Bioengineering Conference (NEBEC), 2012
Articular cartilage is avascular and has limited capacity for repair. In diseased conditions such as osteoarthritis, there is an increase in water content from the average normal of 60-85% to greater than 90%. As cartilage has very little capability for self-repair, methods of early detection of degeneration are required, and assessment of water could prove to be a useful diagnostic ...
2017 11th International Conference on Measurement, 2017
Magnetic resonance (MR) transverse relaxation time (T2) mapping has frequently been used to evaluate collagen content and its organization. In this study, T2 mapping, using novel three-dimensional-triple-echo-steady-state technique was performed in volunteers in-vivo at 7 Tesla under the static load applied by MR compatible compression device. We observed that load of 250 N applied for 12 minutes was sufficient for ...
Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286), 1998
Based on findings from the authors' recent study which showed histologically an earlier tendon to articular cartilage structure incorporation than tendon to bone (BT) in a partial patellectomy model, the authors conducted a pilot study to explore the biological potential of using autologous cartilage as interpositional materials to reestablish a fibrocartilage BT junction zone and to accelerate the BT junction ...
2010 Advanced Technologies for Enhancing Quality of Life, 2010
Management of articular cartilage defects is still one of most challenging problems between orthopedic surgeons. There are some methods which are claiming to restore cartilage around defects but none is capable to restore 100% hyaline cartilage. It is well known that hyaline cartilage has a poor intrinsec capacity of healing and damage from knee trauma or degeneration results in pain ...
Articular cartilage is avascular and has limited capacity for repair. In diseased conditions such as osteoarthritis, there is an increase in water content from the average normal of 60-85% to greater than 90%. As cartilage has very little capability for self-repair, methods of early detection of degeneration are required, and assessment of water could prove to be a useful diagnostic method. Non-destructive near infrared spectroscopy is extremely sensitive to the chemical composition and molecular structure of tissues and could prove to be a useful method for early diagnosis of cartilage degeneration. The hypothesis that NIR spectra can be used to assess water content in cartilage was investigated in the current study.
Magnetic resonance (MR) transverse relaxation time (T2) mapping has frequently been used to evaluate collagen content and its organization. In this study, T2 mapping, using novel three-dimensional-triple-echo-steady-state technique was performed in volunteers in-vivo at 7 Tesla under the static load applied by MR compatible compression device. We observed that load of 250 N applied for 12 minutes was sufficient for in-vivo evaluation of reversible cartilage compression effect. MRI associated with in-vivo compression of cartilage could therefore provide more insight into the mechanical properties of cartilage tissue.
Based on findings from the authors' recent study which showed histologically an earlier tendon to articular cartilage structure incorporation than tendon to bone (BT) in a partial patellectomy model, the authors conducted a pilot study to explore the biological potential of using autologous cartilage as interpositional materials to reestablish a fibrocartilage BT junction zone and to accelerate the BT junction repair. Rabbits were used as experimental model and autologous fibrocartilage (autologous meniscus) and hyaline cartilage (articular cartilage) was used as interpositional materials for BT repair. Earlier and well incorporated BT interface was observed after using both fibrocartilage and hyaline cartilage to repair the BT junction compared with a direct BT reattachment at 8th postoperative week, without degenerative changes. The interpositional cartilage resembled the matrix of the normal fibrocartilage zone of the BT junction by evaluating its matrix proteoglycans using Safranin O staining. However, long-term histological observation and testing mechanical properties of the repaired BT junction via autologous cartilage as the interpositional materials for BT junction repair needs further study.
Management of articular cartilage defects is still one of most challenging problems between orthopedic surgeons. There are some methods which are claiming to restore cartilage around defects but none is capable to restore 100% hyaline cartilage. It is well known that hyaline cartilage has a poor intrinsec capacity of healing and damage from knee trauma or degeneration results in pain and functional impairment. Important untreated cartilage lesions can lead to debilitating joint pain and degenerative arthritis. There are a lot of techniques used to solve this problem. One of these is transplanting hyaline cartilage from a non weight bearing area of the knee joint to the defect situated in weight bearing area. This consists in harvesting multiple small cylindrical autogenousosteocondral plugs from periphery of cartilage and resurfacing the osteocondral defect. (Mosaicplasty or OATS). This technique developed initially by Hangody it is widely used now.
Articular cartilage is an important load bearing surface in joints. Prone to damage and with limited self-repair ability, it is of interest to tissue engineers. Tissue implant design requires full mechanical characterisation of healthy native tissue. A layered organisation of reinforcing collagen fibrils exists in healthy articular cartilage and is believed to be important for correct tissue function. However, the effect of this on the local depth- dependent elasticity is poorly characterised. In this study, quasi-static ultrasound elastography is used both to compare the depth-dependent elastic properties of cartilage structures with two different fibril arrangements and to monitor changes in the elastic properties of engineered samples during development. Results show global and local elastic properties of the native tissues and highlight the differences caused by fibril architecture. At increasing culture periods, results from the engineered tissue demonstrate an increase in elastic stiffness and the time taken to reach equilibrium under a quasi-static displacement. The study suggests suitability of ultrasound elastography for design and monitoring engineered articular cartilage.
The presents the results of laser welding of chicken myocardium. The welding used a continuous diode laser with a wavelength λ = 970 nm and temperature feedback. The laser power varied in the range of 0.2–5 W to stabilize the welding temperature at ~57–62°C. Solders based on water dispersion of bovine serum albumin (BSA 25% w/w), water dispersion of indocyanine green (ICG 0.1% w/w) + BSA 25% w/w and ICG 0.01% w/w + BSA 25% w/w were used. Laser welded seams were examined by optical microscopy and X-ray microtomography. There was shown no defects and the uniformity of the weld formation. Based on the measured absorption spectra of the solders, their optical characteristics were calculated for the radiation λ = 970 nm. The tensile strength of laser welded seams was 0.09±0.04 MPa (BSA), 0.16±0.11 MPa (BSA+ICG 0.01%) and 0.18±0.08 MPa (BSA+ICG 0.1%).
High frequency scanning acoustic microscopy coupled with the Multi Layer Analysis (MLA) method was used to investigate the age-related changes occurring in subchondral bone and cartilage during rat skeletal maturation. Patellae of 6 immature and 7 mature rats were fixed in methanol, cut in the sagittal plane of the patella and imaged in methanol at 400 MHz (3 /spl mu/m spatial resolution) using a scanning acoustic microscope (SAM 2000). Acoustic impedance (Z) images of each sample were constructed using the local measurement of the reflection coefficient. Ultrasound images revealed that calcified cartilage porosity decreased with age and the interface between hyaline and calcified cartilage became more regular. The mean impedance values of mature (5.2 /spl plusmn/ 0.4 MRayl) and immature calcified cartilage and bone (4.9 /spl plusmn/ 0.7 MRayl) were not significantly different. In 6 mature samples, two regions could be distinguished beneath hyaline cartilage: a region corresponding to calcified cartilage where the lower Z (4.6 /spl plusmn/ 0.5 MRayl) may indicate a low mineralized transitional zone between hyaline cartilage and bone; and a region of higher reflection coefficient (Z = 5.4 /spl plusmn/ 0.5 MRayl) and probably higher mineralization in the deeper bone. Current results indicate that quantitative acoustic microscopy may be a new means to investigate changes occurring in the structural organization and mechanical properties of calcified cartilage and bone during the development of diseases like arthritis and osteoarthritis.
Mosaic plasty is a surgery that transplant osteochondral grafts for osteochondritis dissecans. In mosaic plasty, cylindrical osteochondral grafts are harvested from normal area, and transplanted to injured area. The one of the most important thing of this surgery is that the graft should be perpendicular to the surface of the cartilage. The navigation system that aims improvement of precision is already studied, however cannot be applied to use an endoscope. In addition, it is a problem to have bad precision of the transplant in the freehand. Therefore, we thought that the system would widely used if we develop the mosaic plasty navigation system under an endoscope. This study proposes a navigation system to determine a proper position and pose for harvesting. In the experiments, a femoral imitation bone is used as a profile of the femoral joint surface. The experiment consists of the following three procedures: Trace and display of the femoral joint surface profile and a harvester. Display of a normal vector for the femoral joint surface. Measurement of the deviation of the normal vector. In the results, the developed system could display the femoral joint surface and the normal vector for the femoral joint surface virtually. Also, the deviation of the normal vector was an average of 7.27 degrees. As future works, there are to decrease the deviation of the normal vector by improving the precision to acquire the femoral joint surface profile, and to visualize the normal vector for the generated surface.
Rotator cuff tears often occur at the tendon-bone insertion site, a fibrocartilaginous interface that is not regenerated during current repairs. Our aim is to regenerate the insertion site through use of extracellular matrix based scaffolds. In this study, we evaluated the response of mineralized and non-mineralized nanofiber scaffolds to cell culture environment without the influence of cell growth and matrix deposition. We observed minimal change in scaffold mineral content, composition, and chemistry over culture time. Structural properties were influenced, in particular, fiber diameter increased throughout culture. This data is essential for scaffold characterization and understanding cell-material interactions.
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Musculoskeletal Biology - Postdoctoral Researcher
Lawrence Livermore National Laboratory