Embolization

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Embolization is a non-surgical, minimally-invasive procedure performed by an interventional radiologist and interventional neuroradiologists. (Wikipedia.org)






Conferences related to Embolization

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2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

The conference program will consist of plenary lectures, symposia, workshops andinvitedsessions of the latest significant findings and developments in all the major fields ofbiomedical engineering.Submitted papers will be peer reviewed. Accepted high quality paperswill be presented in oral and postersessions, will appear in the Conference Proceedings and willbe indexed in PubMed/MEDLINE & IEEE Xplore


2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI)

The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging.ISBI 2019 will be the 16th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2019 meeting will continue this tradition of fostering cross fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.


2019 IEEE International Ultrasonics Symposium (IUS)

The conference covers all aspects of the technology associated with ultrasound generation and detection and their applications.


2019 International Conference on Robotics and Automation (ICRA)

Flagship conference of the robotics and automation society, a premiere international venue for international robotics researchers


2017 International Symposium on Micro-NanoMechatronics and Human Science (MHS)

The emphasis of this symposium is on fusions of several different fields and applications of micro-nanomechatronics technologies and human sciences. The symposium focus will be on engineering issues related to broader spectra, ranging from basic applications in robots, actuators, sensors, semiconductors, automobiles, and machine tools to new applications in biomedical systems and life sciences. The conference will feature Plenary, Invited, and Contributed papers (oral and poster sessions).


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Periodicals related to Embolization

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Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


Engineering in Medicine and Biology Magazine, IEEE

Both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence. Special interest departments, students, law, clinical engineering, ethics, new products, society news, historical features and government.


Magnetics, IEEE Transactions on

Science and technology related to the basic physics and engineering of magnetism, magnetic materials, applied magnetics, magnetic devices, and magnetic data storage. The Transactions publishes scholarly articles of archival value as well as tutorial expositions and critical reviews of classical subjects and topics of current interest.


Medical Imaging, IEEE Transactions on

Imaging methods applied to living organisms with emphasis on innovative approaches that use emerging technologies supported by rigorous physical and mathematical analysis and quantitative evaluation of performance.


Quantum Electronics, IEEE Journal of

Generation, amplification, modulation, detection, waveguiding, or techniques and effects that can affect the propagation characteristics of coherent electromagnetic radiation having submillimeter and shorter wavelengths


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Most published Xplore authors for Embolization

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Xplore Articles related to Embolization

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Neck localization and geometry quantification of intracranial aneurysms

2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2010

We present an approach for accurate localization of the neck of intracranial aneurysms and quantification of their geometry that is useful for their treatment through endovascular embolization. In particular, we first obtain a vessel segmentation using a topology-preserving level set method and extract the surface of the segmented vessel. We then separate the aneurysm from the parent vessels and localize ...


Endovascular embolization of arteriovenous malformations by bi-directional injection of a biocompatible two component polymer

Proceedings of the First Joint BMES/EMBS Conference. 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Annual Fall Meeting of the Biomedical Engineering Society (Cat. N, 1999

Preliminary studies strongly suggest that biocompatible and mechanically stable embolizing two component polymers can be selectively delivered to cerebral arteriovenous malformations (AVMs) using a bi-directional endovascular injection technique. A computer model and two vascular graft models have been developed to simulate the proposed injection from positions both proximal and distal to the AVM. The current project further developed and optimized ...


Ultrasound characterization of slow precipitating implants for vascular occlusion

2017 IEEE International Ultrasonics Symposium (IUS), 2017

A frequently utilized clinical treatment for liver cancer is the administration of drug eluting microspheres that embolize tumor vasculature depriving it of oxygen and nutrients. However, these beads are fairly large, leading to embolization far away from the tumor and reducing drug penetration. As an alternative, we have developed a slow precipitating in situ forming implant (ISFI) capable of deeper ...


Angiographic flow measurements in neuroembolization procedures

Proceedings of 16th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1994

The objective of embolization is to selectively block or reduce blood flow through abnormal vascular structures. It is desirable to quantitate blood flow, and the authors are investigating appearance time and first pass distribution analysis (FPA) algorithms applied to angiographic image sequences. The emphasis is on developing a practical method for relative flow measurement that can be provided during a ...


Image-based simulation of brain arteriovenous malformation hemodynamics

2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2008

A novel image-based patient-specific simulation method has been developed incorporating computational fluid dynamics (CFD) and porous media principles which presents, for the first time, patient-specific blood flow through an arteriovenous malformation of the brain (BAVM). The new approach constructs an image-based geometric model of a malformation where the BAVM nidus is modelled as a porous medium. The method has been ...


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Educational Resources on Embolization

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IEEE.tv Videos

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IEEE-USA E-Books

  • Neck localization and geometry quantification of intracranial aneurysms

    We present an approach for accurate localization of the neck of intracranial aneurysms and quantification of their geometry that is useful for their treatment through endovascular embolization. In particular, we first obtain a vessel segmentation using a topology-preserving level set method and extract the surface of the segmented vessel. We then separate the aneurysm from the parent vessels and localize its neck by formulating the aneurysm segmentation problem as an s-t minimum cut problem. Finally, we estimate clinically relevant geometric parameters of the aneurysm. The results indicate that there is good agreement between the measurements obtained by the proposed approach and two independent manual sets of measurements obtained by two experienced interventional neuroradiologists.

  • Endovascular embolization of arteriovenous malformations by bi-directional injection of a biocompatible two component polymer

    Preliminary studies strongly suggest that biocompatible and mechanically stable embolizing two component polymers can be selectively delivered to cerebral arteriovenous malformations (AVMs) using a bi-directional endovascular injection technique. A computer model and two vascular graft models have been developed to simulate the proposed injection from positions both proximal and distal to the AVM. The current project further developed and optimized the bi-directional injection technique and evaluated the long-term properties of the embolization polymer. Tissue reactivity and endovascular biocompatibility of the liquid and solid forms of the polymer injectate, as well as the mechanical response of the polymer plug were tested in vivo. The polymer tests helped confirm that the current polymer candidate calcium alginate, (sodium alginate reacted with calcium chloride to form calcium alginate) is a safe, stable, and biocompatible material. Purified sodium alginate polymer, with a high guluronic acid content, has the potential to form a mechanically stable and biocompatible endovascular plug.

  • Ultrasound characterization of slow precipitating implants for vascular occlusion

    A frequently utilized clinical treatment for liver cancer is the administration of drug eluting microspheres that embolize tumor vasculature depriving it of oxygen and nutrients. However, these beads are fairly large, leading to embolization far away from the tumor and reducing drug penetration. As an alternative, we have developed a slow precipitating in situ forming implant (ISFI) capable of deeper penetration and embolization, which we hypothesize will result in better treatment efficacy. In this study, ultrasound was utilized to determine precipitation kinetics of ISFI formulations formulated with varying solvent polarity and polymer molecular weight. Increasing polymer molecular weight from 15 kDa to 53 kDa led to a significant increase in precipitation rate after 5 minutes. A decrease in solvent polarity also led to a significantly higher precipitation rate, which was unexpected, but may be due to attenuation in polymer-rich and polymer-lean microdomains created with a low polar solvent. Tissue mimicking single channel phantoms were then used to determine occlusion distances. An increase in polymer molecular weight to 53kDa was the best formulation meeting both the aforementioned criteria. This study demonstrates, for the first time, ultrasound can be used non-invasively to monitor precipitation kinetics ISFIs to better predict vascular embolization.

  • Angiographic flow measurements in neuroembolization procedures

    The objective of embolization is to selectively block or reduce blood flow through abnormal vascular structures. It is desirable to quantitate blood flow, and the authors are investigating appearance time and first pass distribution analysis (FPA) algorithms applied to angiographic image sequences. The emphasis is on developing a practical method for relative flow measurement that can be provided during a procedure. Preliminary results include color-coded images of arrival times that give a very useful visualization.<<ETX>>

  • Image-based simulation of brain arteriovenous malformation hemodynamics

    A novel image-based patient-specific simulation method has been developed incorporating computational fluid dynamics (CFD) and porous media principles which presents, for the first time, patient-specific blood flow through an arteriovenous malformation of the brain (BAVM). The new approach constructs an image-based geometric model of a malformation where the BAVM nidus is modelled as a porous medium. The method has been applied to a brain BAVM case with two feeding and four draining vessels. A qualitative comparison of the simulation results with blood flow imaging data shows the promise of the approach and suggests that the method may find application in planning for BAVM treatment.

  • Use of 2-hydroxyethyl methacrylate as a solidifying monomer in balloon embolization is a dangerous affair

    The thermochemistry of the polymerization of HEMA using redox catalysts reported to be useful for the polymerization of HEMA in latex balloons in detachable balloon embolization techniques was investigated. With benzoyl peroxide and N,N-dimethyl paratoluidine as the redox system, the temperature rise was more than 100 /spl deg/C during polymerization. Polymerizing HEMA in the presence of poly(vinyl alcohol) (PVA) and employing a judicious combination of catalysts and cross-linking agents were found to reduce the exotherm to obtain soft and rubbery gels.

  • CTA-based angle selection for diagnostic and interventional angiography of saccular intracranial aneurysms

    Coil embolization is a safe treatment for cerebral aneurysms only if the width of the neck in relation to the fundus of the aneurysm is small. Therefore, accurate visualization of the aneurysmal neck is required both in the diagnostic process and during the intervention. Conventional digital subtraction angiography (DSA) is still the preferred modality for the examination of cerebrovascular abnormalities like aneurysms, but it often does not provide the required morphological characteristics due to the suboptimal selection of projection angles and resulting overprojections of surrounding vasculature. This paper presents a method for performing a computer-assisted calculation of the optimal projection angles for DSA by post-processing computed tomographic angiography (CTA) volume data using ray-casting techniques and a combination of image processing algorithms. By means of phantom studies, retrospective simulations of angiograms, and in vivo applications of calculated optimal viewing angles, it is demonstrated that the proposed method results in better angiographic projections of the neck of saccular aneurysms with small neck-fundus ratio than those acquired at standard angles prescribed by clinical protocols.

  • Characterization of compressibility in alginate microspheres

    Embolization is a significant procedure in the occlusion of blood vessel prevent blood flow to an area of the body, which can effectively shrink a tumor. Embolization provides minimally invasive method for fighting hepatocellular carcinoma and kidney cancer [1]. Alginate microspheres provide a biocompatible, non-toxic, cheap, and easy-made technique for blocking blood flow to cancer cells [2]. In the experiment, we measured the compressibility of the microspheres to see their ability to maintain their structure. We report that lower concentrations of alginate and Calcium Chloride in microspheres correlated with a lack of firmness and compressibility.

  • Registration of a reconstructed arteriovenous malformation (AVM) volume within a magnetic resonance (MR) volume

    The embolization of a cerebral AVM is a delicate operation which requires the complete 3D understanding of the surrounding brain area. The evaluation of the micro catheter position in relation to the healthy brain tissues is crucial before the embolization. We have developed a software prototype on a SUN platform aiming to guide the radiologist during the operation. This prototype constructs a volume from AVM 2D angiographic images and combines it with a MR volume. To reconstruct the AVM volume we use three angiographic images taken 45 degrees apart around the same axis. Finally, merging with the MR volume is accomplished using anatomical references from the nonsubtracted angiographic images and from selected slices of the MR volume.<<ETX>>

  • Development of a 3D display system for biplane cerebral angiography, using a personal computer (PC) system

    To improve the total safety for the biplane cerebral angiographic examination, the authors have developed a new three dimensional (3D) display system. By applying this system, shortening the examination time and reducing the risk of infection and embolization were achieved. The authors added just one Windows- NT based Personal Computer (PC) for 3D reconstruction to an ordinary biplane digital-cine-angiography system. This system can process the images of angiogram extempore in a short time and display the run of arterial vessels to the examiner. Biplane images were taken from the digital-cine-angiography system into the PC through a video display and video capture card. Three dimensional positions were calculated and displayed on a CRT monitor. It took about 30 seconds for the calculation. This system could display instantly the run of arterial vessels from any angle by using the computer mouse. The authors' system doesn't disturb the examination, but helps them to understand the run of the arterial vessels. This system was useful in cases where the arteries wound their way around or overlapped each other.



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