Brachytherapy

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Brachytherapy (from the Greek word βραχυς brachys, meaning "short-distance"), also known as internal radiotherapy, sealed source radiotherapy, curietherapy or endocurietherapy, is a form of radiotherapy where a radiation source is placed inside or next to the area requiring treatment. (Wikipedia.org)






Conferences related to Brachytherapy

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2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC)

The conference program will consist of plenary lectures, symposia, workshops andinvitedsessions of the latest significant findings and developments in all the major fields ofbiomedical engineering.Submitted papers will be peer reviewed. Accepted high quality paperswill be presented in oral and postersessions, will appear in the Conference Proceedings and willbe indexed in PubMed/MEDLINE & IEEE Xplore


2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI)

The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging.ISBI 2019 will be the 16th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2019 meeting will continue this tradition of fostering cross fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.


2019 IEEE International Conference on Image Processing (ICIP)

The International Conference on Image Processing (ICIP), sponsored by the IEEE SignalProcessing Society, is the premier forum for the presentation of technological advances andresearch results in the fields of theoretical, experimental, and applied image and videoprocessing. ICIP 2019, the 26th in the series that has been held annually since 1994, bringstogether leading engineers and scientists in image and video processing from around the world.


2019 IEEE International Conference on Industrial Technology (ICIT)

The scope of the conference will cover, but will not be limited to, the following topics: Robotics; Mechatronics; Industrial Automation; Autonomous Systems; Sensing and artificial perception, Actuators and Micro-nanotechnology; Signal/Image Processing and Computational Intelligence; Control Systems; Electronic System on Chip and Embedded Control; Electric Transportation; Power Electronics; Electric Machines and Drives; Renewable Energy and Smart Grid; Data and Software Engineering, Communication; Networking and Industrial Informatics.


2019 IEEE International Ultrasonics Symposium (IUS)

The conference covers all aspects of the technology associated with ultrasound generation and detection and their applications.


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Periodicals related to Brachytherapy

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Automation Science and Engineering, IEEE Transactions on

The IEEE Transactions on Automation Sciences and Engineering (T-ASE) publishes fundamental papers on Automation, emphasizing scientific results that advance efficiency, quality, productivity, and reliability. T-ASE encourages interdisciplinary approaches from computer science, control systems, electrical engineering, mathematics, mechanical engineering, operations research, and other fields. We welcome results relevant to industries such as agriculture, biotechnology, healthcare, home automation, maintenance, manufacturing, pharmaceuticals, retail, ...


Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


Engineering in Medicine and Biology Magazine, IEEE

Both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence. Special interest departments, students, law, clinical engineering, ethics, new products, society news, historical features and government.


Information Technology in Biomedicine, IEEE Transactions on

Telemedicine, teleradiology, telepathology, telemonitoring, telediagnostics, 3D animations in health care, health information networks, clinical information systems, virtual reality applications in medicine, broadband technologies, and global information infrastructure design for health care.


Instrumentation & Measurement Magazine, IEEE

Applications-oriented material in the field of instrumentation and measurement.


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Most published Xplore authors for Brachytherapy

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Xplore Articles related to Brachytherapy

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A modification and purify method to culture the Schwann cells by adult SD rat

Proceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Vol.20 Biomedical Engineering Towards the Year 2000 and Beyond (Cat. No.98CH36286), 1998

Describes a technique of controlled enzyme digestion of peripheral nerves to obtain a highly purified suspension of Schwann cells. An average of 1.72/spl times/10/sup 7/ cells/ml was obtained from a 1 cm segment of ulnar nerve in the grown-up SD rat. Comparison with conventional technique and simultaneous culture of adventitial tissues from the same nerve confirmed the lack of contamination ...


Radiobiology of pulsed dose rates

Proceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), 2000

Any departure from CLDR will yield an increased biological effect, which is greater for tissues with smaller /spl alpha///spl beta/ ratios and shorter T/sub 1/2/ of repair. The Relative Effectiveness (RE=1+g.d/(/spl beta///spl alpha/)) for late responding tissues will increase more than the RE for early responding tissues including tumors. This could obviously lead to a reduced therapeutic ratio. Fortunately the ...


Design of a simple ultrasound/CT fusion image fusion solution for the evaluation of prostate seed brachytherapy

Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201), 2001

The purpose of this project is to devise a solution that will enable physicians, medical physicists and dosimetrists to quantitatively evaluate the success of prostate brachytherapy procedures. It is proposed that a simple ultrasound/CT image fusion solution can be developed and implemented to improve the current post-surgical evaluation process.


Selective magnetic stimulation of cervical nerve roots with a figure-eight coil

Proceedings of 17th International Conference of the Engineering in Medicine and Biology Society, 1995

We investigated the possibility of selective stimulation of cervical nerve roots in healthy subjects. The skin surface on the anterior neck was divided into 12 portions of 2 cm/spl times/2 cm each. Each portion was stimulated magnetically with a figure-eight coil. Induced eddy currents were downward. M-waves of the infraspinatus, the deltoid, the biceps brachii, the triceps brachii, the extensor ...


Catheter tracking in an interventional photoacoustic surgical system

2016 Conference on Lasers and Electro-Optics (CLEO), 2016

Photoacoustic imaging in surgical systems would be more prominent if the photoacoustic effect could be used for catheter tracking. A piezoelement in a catheter allows it to be localized with respect to tracked photoacoustic spots.


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Educational Resources on Brachytherapy

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IEEE.tv Videos

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IEEE-USA E-Books

  • A modification and purify method to culture the Schwann cells by adult SD rat

    Describes a technique of controlled enzyme digestion of peripheral nerves to obtain a highly purified suspension of Schwann cells. An average of 1.72/spl times/10/sup 7/ cells/ml was obtained from a 1 cm segment of ulnar nerve in the grown-up SD rat. Comparison with conventional technique and simultaneous culture of adventitial tissues from the same nerve confirmed the lack of contamination by fibrocytes.

  • Radiobiology of pulsed dose rates

    Any departure from CLDR will yield an increased biological effect, which is greater for tissues with smaller /spl alpha///spl beta/ ratios and shorter T/sub 1/2/ of repair. The Relative Effectiveness (RE=1+g.d/(/spl beta///spl alpha/)) for late responding tissues will increase more than the RE for early responding tissues including tumors. This could obviously lead to a reduced therapeutic ratio. Fortunately the effect is small (less than 10%) unless doses per pulse greater than 1 Gy are used. Dose-per-pulse is paramount (together with total dose) in determining the biological effect. The effect of between-pulse interval is next in importance, (longer intervals helping therapeutic ratio but not if fewer and larger pulses are used). The influence of duration of pulses and dose-rate within each pulse is less. In tissues with the shortest half-times of repair (less than 0.5 hours) the biological effect will be greater for PDR than for CLDR. The authors show here that there are no consistent differences between half-times for tumors and for normal tissues. The effect of "office-hours" PDR is very close to that of the same size and number of pulses given with standard intervals continuously, because there will be only a few overlong (overnight) intervals compared with many more standard short intervals. Late complications will be ameliorated more than tumor cell kill by increasing the intervals between pulses without increasing their size. Probably the most valuable parts of this Handout are the Tables and the References.

  • Design of a simple ultrasound/CT fusion image fusion solution for the evaluation of prostate seed brachytherapy

    The purpose of this project is to devise a solution that will enable physicians, medical physicists and dosimetrists to quantitatively evaluate the success of prostate brachytherapy procedures. It is proposed that a simple ultrasound/CT image fusion solution can be developed and implemented to improve the current post-surgical evaluation process.

  • Selective magnetic stimulation of cervical nerve roots with a figure-eight coil

    We investigated the possibility of selective stimulation of cervical nerve roots in healthy subjects. The skin surface on the anterior neck was divided into 12 portions of 2 cm/spl times/2 cm each. Each portion was stimulated magnetically with a figure-eight coil. Induced eddy currents were downward. M-waves of the infraspinatus, the deltoid, the biceps brachii, the triceps brachii, the extensor digitorum communis, the flexor carpi ulnaris, the abductor pollicis brevis, and the abductor digiti minimi were monitored. The stimulation of some specific portions evoked M-waves of only the infraspinatus and the deltoid. The infraspinatus and the deltoid are innervated predominantly by the 5th cervical nerve, so these results suggest that the 5th cervical nerve root was selectively stimulated with a figure-eight coil.

  • Catheter tracking in an interventional photoacoustic surgical system

    Photoacoustic imaging in surgical systems would be more prominent if the photoacoustic effect could be used for catheter tracking. A piezoelement in a catheter allows it to be localized with respect to tracked photoacoustic spots.

  • CT image construction of the lung in a totally deflated mode

    A novel technique is proposed to construct CT images of the lung in a totally deflated mode using non-rigid registration and extrapolation. This CT image would be very useful in performing tumor ablative procedures (such as brachytherapy) for the treatment of lung cancer. This is because during such procedures the target lung is almost completely deflated whereas pre-operative images are acquired while the lung is partially inflated. This makes pre- operative images very inaccurate. Given that Ultrasound (US) imaging is very sensitive to residual air in a deflated lung, it is not an effective intra- operative imaging modality by itself. One possible approach for image guided lung brachytherapy is registering low quality intra-operative ultrasound images to high quality lung CT image of the deflated lung constructed using the proposed technique. The technique was applied to an ex-vivo porcine lung and the preliminary results were found to be very encouraging.

  • Enhance endothelial function mediated by antihypertensive treatment improves beat to beat smooth muscle energy dissipation

    There are early alterations in endothelial, arterial function and structure in hypertensive patients. The aim of this study was to evaluate in human essential hypertension, the effects of a combination drug, perindoprilindapamide, on both arterial wall viscosity and endothelial function. Arterial diameter (automatic B mode images analysis) and instantaneous pressure (applanation tonometry) were measured in the common carotid artery. A viscoelastic model was used to derive arterial wall viscosity (/spl eta/) by the hysteresis pressure-diameter loop elimination criteria. Flow mediated dilation (FMD) was evaluated in the brachial artery by comparing arterial diameter at rest and during reactive hyperemia after 5 min of brachial occlusion. After 6 months of treatment, blood pressure levels normalized and FMD improved significantly (p<0.05). Similar behavior was founded in /spl eta/, which represents an intrinsic marker of smooth muscle mechanical performance. In conclusion, our results suggests that in essential hypertension, in the arterial wall, the endothelial dysfunction is associated with an abnormal energy dissipation.

  • 2K-4 Ultrasonic Imaging of Brachytherapy Seeds Based on Singular Spectrum Analysis

    Ultrasound-guided brachytherapy using small titanium-shelled radioactive seeds is an effective means of treating prostate cancer. Unfortunately, implantation using needles inserted transperitoneally causes gland movement and distortion, which often results in dosimetry errors. If actual seed locations could be determined in the operating room, then corrections to dosimetry errors could be made immediately. However, seed specularity, shadowing, and tissue clutter make imaging seeds difficult using conventional ultrasound. Singular spectrum analysis (SSA) shows promise for reliably imaging radioactive seeds implanted in the prostate and enabling additional corrective implantations to be made in the operating room. SSA utilizes eigenvalues derived from the diagonalized correlation matrix of envelope-detected radiofrequency echo signals to yield a P-value indicative of the likelihood of a seed-specific repetitive signal. We demonstrated the potential of SSA for seed detection and imaging and illustrated the trade-off considerations for optimization of SSA in clinical applications using simulations assessing performance as a function of different levels of noise and the presence of repetitive signals with various repetition periods; experiments in an ideal scattering environment; and experiments using seeds implanted in beef

  • Continuous measurement of arterial diameter changes using a wearable and flexible ultrasonic sensor

    Changes in the biomechanical functions of artery serve as important indicators for prediction of cardiovascular disease. Endothelial dysfunction is known to play a role to develop atherosclerosis and cardiovascular disease. Ultrasound measurement of flow-mediated dilation of the brachial artery is a method to quantify endothelial function based on changes in arterial diameter. One challenge of the ultrasonic arterial measurement is the compression of the artery due to the weight of a conventional ultrasound probe employed, resulting in the error on the diameter estimation. One approach to address this issue with low-cost is to use a wearable ultrasound sensor which is flexible and lightweight so that it does not deform the artery of interest beneath the sensor during the measurement. In this paper, the capability of the wearable sensor to measure the change in arterial diameter is investigated.

  • Large-deformation image registration using fluid landmarks

    For each patient receiving definitive treatment for cervix cancer, several CT/MR imaging studies need to be registered in order to specify the total physical or biological dose to each fixed tissue voxel in an organ system. This turns out to be a difficult problem due to large localized deformations and displacements of bladder, rectum, vagina, uterus and paracervical tissues due to tumor regression, bladder and rectal filling variations, and especially insertion of the applicator itself. This paper explores the utility of using the fluid landmark image registration method to register images before and after insertion of the brachytherapy applicator in order to track radiation dose from one treatment to the next.



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