Conferences related to Tissue Engineering

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2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (TRANSDUCERS & EUROSENSORS XXXIII)

The world's premiere conference in MEMS sensors, actuators and integrated micro and nano systems welcomes you to attend this four-day event showcasing major technological, scientific and commercial breakthroughs in mechanical, optical, chemical and biological devices and systems using micro and nanotechnology.The major areas of activity in the development of Transducers solicited and expected at this conference include but are not limited to: Bio, Medical, Chemical, and Micro Total Analysis Systems Fabrication and Packaging Mechanical and Physical Sensors Materials and Characterization Design, Simulation and Theory Actuators Optical MEMS RF MEMS Nanotechnology Energy and Power


2018 18th International Symposium on Antenna Technology and Applied Electromagnetics (ANTEM)

ANTEM's technical sessions will provide a comprehensive and well-balanced program and are intended to provide an international forum for the exchange of information on state-of-the-art research in antennas, propagation, and electromagnetic engineering. Authors are invited to submit contributions for review and possible presentation during the symposium on topics of interest to ANTEM. In addition to regularly scheduled sessions for oral presentations, there will be distinguished lecturers and special sessions. There will be a Student Paper Competition as well as a Technical Exhibition.


2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

The conference program will consist of plenary lectures, symposia, workshops and invitedsessions of the latest significant findings and developments in all the major fields of biomedical engineering.Submitted papers will be peer reviewed. Accepted high quality papers will be presented in oral and postersessions, will appear in the Conference Proceedings and will be indexed in PubMed/MEDLINE


2018 7th IEEE International Conference on Biomedical Robotics and Biomechatronics (Biorob)

The RAS/EMBS International Conference on Biomedical Robotics and Biomechatronics - BioRob 2018 - is a joint effort of the two IEEE Societies of Robotics and Automation - RAS - and Engineering in Medicine and Biology - EMBS.BioRob covers both theoretical and experimental challenges posed by the application of robotics and mechatronics in medicine and biology. The primary focus of Biorobotics is to analyze biological systems from a "biomechatronic" point of view, trying to understand the scientific and engineering principles underlying their extraordinary performance. This profound understanding of how biological systems work, behave and interact can be used for two main objectives: to guide the design and fabrication of novel, high performance bio-inspired machines and systems for many different applications; and to develop novel nano, micro-, macro- devices that can act upon, substitute parts of, and assist human beings in prevention, diagnosis, surgery, prosthetics, rehabilitation.


2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)

The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2018 will be the 15th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2018 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging.ISBI 2019 will be the 16th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2019 meeting will continue this tradition of fostering cross fertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2017 IEEE 14th International Symposium on Biomedical Imaging (ISBI 2017)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2017 will be the 14th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2017 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI 2016)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forumfor the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2016 willbe the thirteenth meeting in this series. The previous meetings have played a leading role in facilitatinginteraction between researchers in medical and biological imaging. The 2016 meeting will continue thistradition of fostering crossfertilization among different imaging communities and contributing to an integrativeapproach to biomedical imaging across all scales of observation.

  • 2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI 2015)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2015 will be the 12th meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2014 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI 2014)

    The IEEE International Symposium on Biomedical Imaging (ISBI) is the premier forum for the presentation of technological advances in theoretical and applied biomedical imaging. ISBI 2014 will be the eleventh meeting in this series. The previous meetings have played a leading role in facilitating interaction between researchers in medical and biological imaging. The 2014 meeting will continue this tradition of fostering crossfertilization among different imaging communities and contributing to an integrative approach to biomedical imaging across all scales of observation.

  • 2013 IEEE 10th International Symposium on Biomedical Imaging (ISBI 2013)

    To serve the biological, biomedical, bioengineering, bioimaging and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2012 IEEE 9th International Symposium on Biomedical Imaging (ISBI 2012)

    To serve the biological, biomedical, bioengineering, bioimaging, and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2011 IEEE 8th International Symposium on Biomedical Imaging (ISBI 2011)

    To serve the biological, biomedical, bioengineering, bioimaging, and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2010 IEEE 7th International Symposium on Biomedical Imaging (ISBI 2010)

    To serve the biological, biomedical, bioengineering, bioimaging, and other technical communities through a quality program of presentations and papers on the foundation, application, development, and use of biomedical imaging.

  • 2009 IEEE 6th International Symposium on Biomedical Imaging (ISBI 2009)

    Algorithmic, mathematical and computational aspects of biomedical imaging, from nano- to macroscale. Topics of interest include image formation and reconstruction, computational and statistical image processing and analysis, dynamic imaging, visualization, image quality assessment, and physical, biological and statistical modeling. Molecular, cellular, anatomical and functional imaging modalities and applications.

  • 2008 IEEE 5th International Symposium on Biomedical Imaging (ISBI 2008)

    Algorithmic, mathematical and computational aspects of biomedical imaging, from nano- to macroscale. Topics of interest include image formation and reconstruction, computational and statistical image processing and analysis, dynamic imaging, visualization, image quality assessment, and physical, biological and statistical modeling. Molecular, cellular, anatomical and functional imaging modalities and applications.

  • 2007 IEEE 4th International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2007)

  • 2006 IEEE 3rd International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2006)

  • 2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2004)

  • 2002 1st IEEE International Symposium on Biomedical Imaging: Macro to Nano (ISBI 2002)


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Periodicals related to Tissue Engineering

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Antennas and Propagation, IEEE Transactions on

Experimental and theoretical advances in antennas including design and development, and in the propagation of electromagnetic waves including scattering, diffraction and interaction with continuous media; and applications pertinent to antennas and propagation, such as remote sensing, applied optics, and millimeter and submillimeter wave techniques.


Antennas and Wireless Propagation Letters, IEEE

IEEE Antennas and Wireless Propagation Letters (AWP Letters) will be devoted to the rapid electronic publication of short manuscripts in the technical areas of Antennas and Wireless Propagation.


Biomedical Circuits and Systems, IEEE Transactions on

The Transactions on Biomedical Circuits and Systems addresses areas at the crossroads of Circuits and Systems and Life Sciences. The main emphasis is on microelectronic issues in a wide range of applications found in life sciences, physical sciences and engineering. The primary goal of the journal is to bridge the unique scientific and technical activities of the Circuits and Systems ...


Biomedical Engineering, IEEE Reviews in

The IEEE Reviews in Biomedical Engineering will review the state-of-the-art and trends in the emerging field of biomedical engineering. This includes scholarly works, ranging from historic and modern development in biomedical engineering to the life sciences and medicine enabled by technologies covered by the various IEEE societies.


Biomedical Engineering, IEEE Transactions on

Broad coverage of concepts and methods of the physical and engineering sciences applied in biology and medicine, ranging from formalized mathematical theory through experimental science and technological development to practical clinical applications.


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Most published Xplore authors for Tissue Engineering

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Xplore Articles related to Tissue Engineering

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Development of scaffold for use in osteochondral tissue engineering

[{u'author_order': 1, u'affiliation': u'Musculoskeletal and Translational Tissue Engineering Research (MATTER) Laboratory, Department of Biomedical Engineering, Rensselaer Polytechnic Institute 110 Eighth Street, Troy, NY 12180, USA', u'full_name': u'G. Clay'}, {u'author_order': 2, u'affiliation': u'Musculoskeletal and Translational Tissue Engineering Research (MATTER) Laboratory, Department of Biomedical Engineering, Rensselaer Polytechnic Institute 110 Eighth Street, Troy, NY 12180, USA', u'full_name': u'S. Modha'}, {u'author_order': 3, u'affiliation': u'Musculoskeletal and Translational Tissue Engineering Research (MATTER) Laboratory, Department of Biomedical Engineering, Rensselaer Polytechnic Institute 110 Eighth Street, Troy, NY 12180, USA', u'full_name': u'P. Schomacker'}, {u'author_order': 4, u'affiliation': u'Musculoskeletal and Translational Tissue Engineering Research (MATTER) Laboratory, Department of Biomedical Engineering, Rensselaer Polytechnic Institute 110 Eighth Street, Troy, NY 12180, USA', u'full_name': u'J. A. Cooper'}] 2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), 2015

In this study, the bone component of a bi-phasic scaffold was developed and mechanically tested to compare it to that of subchondral bone properties. The bone component was composed of poly (ε-caprolactone):poly (ethylene oxide):sucrose (PCL:PEO:sucrose) that exhibited both pore size and porosity similar to that of cancellous bone, thereby providing a similar mechanical structure for the osteoblasts to differentiate and ...


Direct laser writing of polylactide 3D scaffolds for neural tissue engineering applications

[{u'author_order': 1, u'affiliation': u'Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), N. Plastira 100, 70013, Heraklion, Crete, Greece', u'full_name': u'V. Melissinaki'}, {u'author_order': 2, u'affiliation': u'University of Sheffield, Materials Science and Engineering Department, Biomaterials and Tissue Engineering Group, Kroto Research Institute, Broad Lane, S3 7HQ, United Kingdom', u'full_name': u'A.A. Gill'}, {u'author_order': 3, u'affiliation': u'University of Sheffield, Materials Science and Engineering Department, Biomaterials and Tissue Engineering Group, Kroto Research Institute, Broad Lane, S3 7HQ, United Kingdom', u'full_name': u'I. Ortega'}, {u'author_order': 4, u'affiliation': u'Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), N. Plastira 100, 70013, Heraklion, Crete, Greece', u'full_name': u'M. Vamvakaki'}, {u'author_order': 5, u'affiliation': u'Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), N. Plastira 100, 70013, Heraklion, Crete, Greece', u'full_name': u'A. Ranella'}, {u'author_order': 6, u'affiliation': u'Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), N. Plastira 100, 70013, Heraklion, Crete, Greece', u'full_name': u'C. Fotakis'}, {u'author_order': 7, u'affiliation': u'Institute of Electronic Structure and Laser (IESL), Foundation for Research and Technology Hellas (FORTH), N. Plastira 100, 70013, Heraklion, Crete, Greece', u'full_name': u'M. Farsari'}, {u'author_order': 8, u'affiliation': u'University of Sheffield, Materials Science and Engineering Department, Biomaterials and Tissue Engineering Group, Kroto Research Institute, Broad Lane, S3 7HQ, United Kingdom', u'full_name': u'F. Claeyssens'}] 2011 Conference on Lasers and Electro-Optics Europe and 12th European Quantum Electronics Conference (CLEO EUROPE/EQEC), 2011

Here, we investigate the relationship between scaffold topology and cell growth of neural cells on 3D scaffolds fabricated using Direct fs Laser Writing (DLW) of a polylactide-based material. DLW has been demonstrated as a technology for the fabrication of 3D structures with high resolution . The technique is based on the phenomenon of multi-photon polymerization. When the beam of an ...


Cellular/tissue engineering - Cardiomyoplasty: The prospect of human stem cells

[{u'author_order': 1, u'affiliation': u'Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA', u'full_name': u'D.M. Pedrotty'}, {u'author_order': 2, u'affiliation': u'Dept. of Biomed. Eng., Duke Univ., Durham, NC, USA', u'full_name': u'N. Bursac'}] IEEE Engineering in Medicine and Biology Magazine, 2005

Currently, the largest ongoing effort in cellular and tissue cardiomyoplasty therapies is the search for a suitable cell source. The following are the desirable attributes of an ideal cell source: 1) autologous (not requiring immune suppression), 2) able to substantially proliferate in vitro, 3) having a similar function when compared to host cardiomyocytes, and 4) able to couple with the ...


Temporal and spatial control over soluble protein signaling for musculoskeletal tissue engineering

[{u'author_order': 1, u'affiliation': u'University of Wisconsin, Madison, WI 53706 USA', u'full_name': u'William L. Murphy'}] 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2009

Orthopedic tissue engineering strategies have developed rapidly in response to large and growing clinical needs. However, current clinical methods for replacement of natural tissue function have significant limitations, and pragmatic challenges have hindered clinical use of emerging tissue engineering approaches. In addition, current methods are not yet capable of achieving complex spatial and temporal regulation of soluble signaling (e.g. growth ...


In vitro Degradation Behavior of Photopolymerized PEG Hydrogels as Tissue Engineering Scaffold

[{u'author_order': 1, u'affiliation': u'Columbia University, Dental Medicine and Biomedical Engineering, New York City, NY 10032', u'full_name': u'Antonio X. Xin'}, {u'author_order': 2, u'affiliation': u'Columbia University, Dental Medicine and Biomedical Engineering, New York City, NY 10032', u'full_name': u'Celeste Gaydos'}, {u'author_order': 3, u'affiliation': u'Columbia University, Dental Medicine and Biomedical Engineering, New York City, NY 10032', u'full_name': u'Jeremy J. Mao'}] 2006 International Conference of the IEEE Engineering in Medicine and Biology Society, 2006

PEGDA was photopolymerized to form hydrogels under different UV light irradiation times. In order to investigate the degradation rate in vitro, the various PEGDA hydrogels were incubated in PBS solution at 37degC in shaking water bath system. The physical-chemical properties such as pH values, dimension, mass and volume change, compressive strength and Young's modulus were measured. MALDI-MS and SEM were ...


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eLearning

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IEEE.tv Videos

EMBC 2011-Workshop-Nanobiomaterials-Rohin K. Iyer
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ASC-2014 SQUIDs 50th Anniversary: 2 of 6 - John Clarke - The Ubiquitous SQUID
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2014 Medal in Power Engineering
IMS 2012 Special Sessions: Globalization of Engineering Education and Research: Opportunities and Challenges - Alan Cheville
IMS 2012 Special Sessions: Globalization of Engineering Education and Research: Opportunities and Challenges - Sigrid Berka
2011 IEEE Medal in Power Engineering - William F. Tinney
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IMS 2015: Luca Pierantoni - A New Challenge in Computational Engineering
Wiley Press / IEEE Power Engineering Series-Power Engineering Series
IMS 2012 Special Sessions: A Retrospective of Field Theory in Microwave Engineering - Magdalena Salazar Palma
IMS 2012 Special Sessions: Globalization of Engineering Education and Research: Opportunities and Challenges - Ron Hira

IEEE-USA E-Books

  • Biologic Foundations for Skeletal Tissue Engineering

    Tissue engineering research for bone and joint applications entails multidisciplinary teams bringing together the needed expertise in anatomy, biology, biochemistry, pathophysiology, materials science, biomechanics, fluidics, and clinical and veterinary orthopedics. It is the goal of this volume to provide students and investigators who are entering this exciting area with an understanding of the biologic foundations necessary to appreciate the problems in bone and cartilage that may benefit from innovative tissue engineering approaches. This volume includes state-of-the-art information about bone and cartilage physiology at the levels of cell and molecular biology, tissue structure, developmental processes, their metabolic and structural functions, responses to injury, mechanisms of post-natal healing and graft incorporation, the many congenital and acquired disorders, effects of aging, and current clinical standards of care. It reviews the strengths and limitations of various experimental animal models, sources of cells, composition and design of scaffolds, activities of growth factors and genes to enhance histogenesis, and the need for new materials in the context of cell- based and cell-free tissue engineering. These building blocks constitute the dynamic environments in which innovative approaches are needed for addressing debilitating disorders of the skeleton. It is likely that a single tactic will not be sufficient for different applications because of variations in the systemic and local environments. The realizations that tissue regeneration is complex and dynamic underscore the continuing need for innovative multidisciplinary investigations, with an eye to simple and safe therapies for disabled patients. Table of Contents: Introduction / Structure and Function of Bone and Cartilage Tissue / Development / Responses to Injury and Grafting / Clinical Applications for Skeletal Tissue Engineering / Animal Models / Tissue Engineering Principles for Bone and Cartilage / Perspectives

  • Central Nervous System Tissue Engineering: Current Considerations and Strategies

    Combating neural degeneration from injury or disease is extremely difficult in the brain and spinal cord, i.e. central nervous system (CNS). Unlike the peripheral nerves, CNS neurons are bombarded by physical and chemical restrictions that prevent proper healing and restoration of function. The CNS is vital to bodily function, and loss of any part of it can severely and permanently alter a person's quality of life. Tissue engineering could offer much needed solutions to regenerate or replace damaged CNS tissue. This review will discuss current CNS tissue engineering approaches integrating scaffolds, cells and stimulation techniques. Hydrogels are commonly used CNS tissue engineering scaffolds to stimulate and enhance regeneration, but fiber meshes and other porous structures show specific utility depending on application. CNS relevant cell sources have focused on implantation of exogenous cells or stimulation of endogenous populations. Somatic cells of the CNS are rarely utilized for tissue engineering; however, glial cells of the peripheral nervous system (PNS) may be used to myelinate and protect spinal cord damage. Pluripotent and multipotent stem cells offer alternative cell sources due to continuing advancements in identification and differentiation of these cells. Finally, physical, chemical, and electrical guidance cues are extremely important to neural cells, serving important roles in development and adulthood. These guidance cues are being integrated into tissue engineering approaches. Of particular interest is the inclusion of cues to guide stem cells to differentiate into CNS cell types, as well to guide neuron targeting. This review should provide the reader with a broad understanding of CNS tissue engineering challenges and tactics, with the goal of fostering the future development of biologically inspired designs. Table of Contents: Introduction / Anatomy of the CNS and Progression of Neurological Damage / Biomaterials for Scaffold Preparation / Cell Sources for CNS TE / Stimulation and Guidance / Concluding Remarks

  • Cardiac Tissue Engineering: Principles, Materials, and Applications

    Cardiac tissue engineering aims at repairing damaged heart muscle and producing human cardiac tissues for application in drug toxicity studies. This book offers a comprehensive overview of the cardiac tissue engineering strategies, including presenting and discussing the various concepts in use, research directions and applications. Essential basic information on the major components in cardiac tissue engineering, namely cell sources and biomaterials, is firstly presented to the readers, followed by a detailed description of their implementation in different strategies, broadly divided to cellular and acellular ones. In cellular approaches, the biomaterials are used to increase cell retention after implantation or as scaffolds when bioengineering the cardiac patch, in vitro. In acellular approaches, the biomaterials are used as ECM replacement for damaged cardiac ECM after MI, or, in combination with growth factors, the biomaterials assume an additional function as a depot for prolonged factor activity for the effective recruitment of repairing cells. The book also presents technological innovations aimed to improve the quality of the cardiac patches, such as bioreactor applications, stimulation patterns and prevascularization. This book could be of interest not only from an educational perspective (i.e. for graduate students), but also for researchers and medical professionals, to offer them fresh views on novel and powerful treatment strategies. We hope that the reader will find a broad spectrum of ideas and possibilities described in this book both interesting and convincing. Table of Contents: Introduction / The Heart: Structure, Cardiovascular Diseases, and Regeneration / Cell Sources for Cardiac Tissue Engineering / Biomaterials: Polymers, Scaffolds, and Basic Design Criteria / Biomaterials as Vehicles for Stem Cell Delivery and Retention in the Infarct / Bioengineering of Cardiac Patches, In Vitro / Perfusion Bioreactors and Stimulation Patterns in Cardiac Tissue Engineering / Vascularization of Cardiac Patches / Acellular Biomaterials for Cardiac Repair / Biomaterial-based Controlled Delivery of Bioactive Molecules for Myocardial Regeneration

  • Tissue Engineering of Temporomandibular Joint Cartilage

    The temporomandibular joint (TMJ) is a site of intense morbidity for millions of people, especially young, pre-menopausal women. Central to TMJ afflictions are the cartilaginous tissues of the TMJ, especially those of the disc and condylar cartilage, which play crucial roles in normal function of this unusual joint. Damage or disease to these tissues significantly impacts a patient's quality of life by making common activities such as talking and eating difficult and painful. Unfortunately, these tissues have limited ability to heal, necessitating the development of treatments for repair or replacement. The burgeoning field of tissue engineering holds promise that replacement tissues can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical, biochemical, and anatomical characteristics of the disc and condylar cartilage, and also provides a historical perspective of past and current TMJ treatments and previous tissue engineering efforts. This book was written to serve as a reference for researchers seeking to learn about the TMJ, for undergraduate and graduate level courses, and as a compendium of TMJ tissue engineering design criteria. Table of Contents: The Temporomandibular Joint / Fibrocartilage of the TMJ Disc / Cartilage of the Mandibular Condyle / Tissue Engineering of the Disc / Tissue Engineering of the Mandibular Condyle / Current Perspectives

  • Fundamental Biomechanics in Bone Tissue Engineering

    This eight-chapter monograph intends to present basic principles and applications of biomechanics in bone tissue engineering in order to assist tissue engineers in design and use of tissue-engineered products for repair and replacement of damaged/deformed bone tissues. Briefly, Chapter 1 gives an overall review of biomechanics in the field of bone tissue engineering. Chapter 2 provides detailed information regarding the composition and architecture of bone. Chapter 3 discusses the current methodologies for mechanical testing of bone properties (i.e., elastic, plastic, damage/fracture, viscoelastic/viscoplastic properties). Chapter 4 presents the current understanding of the mechanical behavior of bone and the associated underlying mechanisms. Chapter 5 discusses the structure and properties of scaffolds currently used for bone tissue engineering applications. Chapter 6 gives a brief discussion of current mechanical and structural tests of repair/tissue engineered bone tissues. Chapter 7 summarizes the properties of repair/tissue engineered bone tissues currently attained. Finally, Chapter 8 discusses the current issues regarding biomechanics in the area of bone tissue engineering. Table of Contents: Introduction / Bone Composition and Structure / Current Mechanical Test Methodologies / Mechanical Behavior of Bone / Structure and Properties of Scaffolds for Bone Tissue Regeneration / Mechanical and Structural Evaluation of Repair/Tissue Engineered Bone / Mechanical and Structural Properties of Tissues Engineered/Repair Bone / Current Issues of Biomechanics in Bone Tissue Engineering

  • Articular Cartilage Tissue Engineering

    Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis (OA) are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. Table of Contents: Hyaline Articular Cartilage / Cartilage Aging and Pathology / In Vitro / Bioreactors / Future Directions

  • Bladder Tissue Engineering

    We provide a description of the structure and function of the mammalian bladder. This is followed by a discussion of medical conditions and current treatment modalities. We then provide specific examples of tissue engineering as it applies to fabricating the bladder.

  • Tracheal Tissue Engineering

    We provide a description of the structure and function of the mammalian trachea. This is followed by a discussion of medical conditions and current treatment modalities. We then provide specific examples of tissue engineering as it applies to fabricating the trachea.

  • Bioreactors for Tissue Engineering

    We introduce the concept of bioreactors as applied to the tissue and organ fabrication process. We begin by providing a framework for bioreactors, provide a definition and describe a classification for bioreactors. We provide specific examples of bioreactors for cell culture, biomaterial synthesis, scaffold cellularization, mechanical stretch, electrical stimulation and perfusion.

  • Liver Tissue Engineering

    We provide a description of the structure and function of the mammalian liver. This is followed by a discussion of medical conditions and current treatment modalities. We then provide specific examples of tissue engineering as it applies to fabricating the liver.



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